Influence of preoperative comorbidities and nutrition status on elderly patients with oral squamous cell carcinoma

doi:10.19438/j.cjoms.2017.03.009

Abstract

Abstract: PURPOSE: To evaluate the influence of pre-operative comorbidities and nutrition status on elderly patients with oral squamous cell carcinoma (OSCC). METHODS: The data of elderly patients with OSCC treated between January 2010 to December 2012 in the Department of Oromaxillofacial Head and Neck Oncology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine was analyzed. Patients who were histologically diagnosed as squamous cell carcinoma, aged over 60 years and surgically managed were included. The comorbidity index including Charlson, HNCA and ACT index and nutrition index (NI) were analyzed. RESULTS: Among 465 patients, preoperative Charlson, HNCA and ACT index didn't show significant impact on outcome of disease (P=0.747, 0.530, 0.869). Preoperative nutrition status and nutrition index were independent factors for prediction of prognosis (P<0.001). CONCLUSIONS: For elderly patients with OSCC, preoperative systemic disease is not a predictive factor for prognosis; however, the worse the preoperative nutritional status, the lower the survival rate.

Key words: Elderly patients, Oral squamous cell carcinoma, Nutrition status, Prognosis

CLC Number:

R739.8

LIU Zhe-qi, CAO Wei, REN Zhen-hu, PENG Can-bang, JI Tong, WANG Yue-ping.. Influence of preoperative comorbidities and nutrition status on elderly patients with oral squamous cell carcinoma[J]. China Journal of Oral and Maxillofacial Surgery, 2017, 15(3): 235-239.

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