Clinicopathological characteristics and prognostic analysis of oral squamous cell carcinoma with parotid lymph node metastasis

doi:10.19438/j.cjoms.2022.01.005

Abstract

Abstract: PURPOSE: To investigate the clinical regularity of oral squamous cell carcinoma(OSCC) with parotid lymph node metastasis and its influence on prognosis. METHODS: A retrospective analysis of the clinicopathological data of 60 oral squamous cell carcinoma patients with or without parotid lymph node metastasis admitted to Shanghai Ninth People's Hospital of Shanghai Jiao Tong University School of Medicine from January 2003 to December 2017 was conducted. SPSS 23.0 software package was used for data analysis. RESULTS: Primary tumor T stage(P=0.022) and cervical lymph node status(N stage, P=0.008) were closely related to parotid lymph node metastasis. Parotid metastatic lymph nodes were mostly located in the lower pole of the superficial parotid gland and prone to extracellular invasion(P<0.05). Parotid gland lymph node metastasis is closely related to the prognosis of oral squamous cell carcinoma(P=0.0004), and the 5-year survival rate of gingival squamous cell carcinoma with parotid lymph node metastasis was significantly higher than that of tongue squamous cell carcinoma(P=0.0427). CONCLUSIONS: Parotid lymph node metastasis is a poor prognostic factor for oral squamous cell carcinoma. Higher T and N stages are two important factors that promote LN metastasis to parotid gland in OSCC patients.

Key words: Oral squamous cell carcinoma, Parotid lymph node, Metastasis, Prognosis

CLC Number:

R739.8

LI Xing, XU Fei-hu, YANG Yun-bo, HAN Nan-nan, RUAN Min. Clinicopathological characteristics and prognostic analysis of oral squamous cell carcinoma with parotid lymph node metastasis[J]. China Journal of Oral and Maxillofacial Surgery, 2022, 20(1): 28-31.

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