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    Expert consensus on diagnosis and clinical management of medication-related osteonecrosis of the jaw
    HE Yue, CHEN Heng, AN Jin-gang, GUO Yu-xing, PAN Jian, TIAN Lei, LIU Bing, HOU Jin-song, LI Jin-song, JIANG Can-hua, LI Meng-yu, TIAN Zhen, XU Jie, ZHU Ling, SUN Chang-fu, ZHI Ke-qian, QU Qing, ZONG Chun-lin, SUN Jing-jing, ZHANG Zhi-yuan
    China Journal of Oral and Maxillofacial Surgery    2023, 21 (4): 313-325.   DOI: 10.19438/j.cjoms.2023.04.001
    Abstract2888)      PDF (2051KB)(2683)      
    Medication-related osteonecrosis of the jaw(MRONJ) is a complication caused by the application of anti-resorptive medications, angiogenesis inhibitors, hormones and other medications for the treatment of some systemic diseases. The clinical symptoms include swelling, pain, masticatory disorders, persistent fistula, bone exposure and even pathological fracture, which seriously affect the patients' quality of life. Domestically, there is a lack of consensus or guidelines on classification, staging and treatment of MRONJ, and different institutions make diagnosis and treatment plans empirically. In order to unify and standardize the diagnosis and treatment of MRONJ and improve the prognosis, an expert panel of MRONJ research from 12 famous domestic medical colleges and affiliated hospitals convened a meeting to discuss the diagnosis and treatment opinions of MRONJ. Meanwhile, consensus recommendations were also revised with a comprehensive literature review of the previous treatment experiences and research findings. Finally, this expert consensus was finished for clinical references.
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    Application of modified Kuwata’s drinking water swallow test in swallowing function screening for patients with oral cancer after surgery
    HE Xing-fang, WANG Shuai, DENG Yi-jun, LIN Zhu-mei, HUANG Qiu-yu
    China Journal of Oral and Maxillofacial Surgery    2025, 23 (1): 24-28.   DOI: 10.19438/j.cjoms.2025.01.005
    Abstract1581)      PDF (780KB)(311)      
    PURPOSE: To analyze the application effect of modified Kuwata's water swallow test in the swallowing function of patients after repair and reconstruction surgery as screening for oral cancer. METHODS: A total of 120 patients with oral cancer who underwent repair and reconstruction in our hospital from June 2020 to June 2022 were selected as the research subjects, and they were divided into control group and experimental group by random number table, with 60 cases in each group. The patients in the experimental group were screened and evaluated by modified Kuwata's water swallow test, while patients in the control group were screened by Kuwata's water swallow test. The two groups were compared with the number of evaluations, the rate of gastric tube removal, the rate of gastric tube replacement, and duration of gastric tube indwelling. SPSS 22.0 software package was used for data analysis. RESULTS: The number of evaluations, the rate of gastric tube repositioning, and the duration of gastric tube indwelling in the experimental group were significantly lower than those in the control group(P<0.05), and the gastric tube removal rate in the experimental group was significantly higher than that in the control group(P<0.05). CONCLUSIONS: Modified Kuwata's water swallow test is safer and efficacy than water swallow test of swallowing function screening in postoperative patients with oral cancer, and it is worthy of clinical implementation.
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    Chinese expert consensus on salvage surgery for advanced or recurrent oral(oropharyngeal) cancers
    HE Yue, ZHU Feng-shuo, MA Chun-yue, HE Jie, WANG Yan-an, LI Jin-song, LIU Bing, JIANG Can-hua, HOU Jin-song, PENG Xin, HE Pei-jie, ZHANG Dong-sheng, WANG Jun, LIU Xi-qiang, YANG Hong-yu, CHEN Chao-gang, WU Yi-qun, YAO Yuan, SU Li-xin, LIU Feng, MA Yu-bo, ZHU Ling, WEN Hong-mei, HUANG Qiu-yu
    China Journal of Oral and Maxillofacial Surgery    2024, 22 (6): 521-528.   DOI: 10.19438/j.cjoms.2024.06.001
    Abstract1527)      PDF (1848KB)(442)      
    Oral(oropharyngeal) cancer is a type of malignant tumors of the head and neck with the highest incidence. Many patients have been clinically advanced, and most of them need to be treated by surgery combined with radiotherapy and chemotherapy. Many patients with oral(oropharyngeal) cancer will have local recurrence or metastasis after the first surgical or chemoradiotherapy, and the second treatment is more difficult with the poor prognosis. How to effectively treat these patients with advanced or recurrent oral(oropharyngeal) cancer has become the focus of clinical attention. However, there is no basis to follow about how to carry out therapeutic surgical treatment, and non-standard diagnosis and treatment are also common. Therefore, we formulated this consensus in the fields of definition, indications, perioperative evaluation, surgical classification, adjuvant therapy, functional rehabilitation and other fields of advanced or recurrent oral (oropharyngeal) cancer, based on evidence-based medical evidence and national maxillofacial head and neck surgery expert suggestion, for reference by oral and maxillofacial, and head & neck surgeons across the country.
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    Application and advancement of minimally invasive instruments and micro-power devices in tooth extraction
    LI Yan-xiang, YAN Li-jun, LING Xiao-wan, ZHOU Wen-jie, WANG Yue-ping
    China Journal of Oral and Maxillofacial Surgery    2023, 21 (2): 191-196.   DOI: 10.19438/j.cjoms.2023.02.016
    Abstract1151)      PDF (914KB)(792)      
    Tooth extraction is to remove the affected teeth that can no longer provide oral function, and it is also one of the most basic and common procedures in alveolar surgery. Conventional tooth extraction applies elevators, forceps, chisels and other instruments, which may cause severe physical and psychological trauma to the patient. In recent years, the concepts of minimally invasive tooth extraction has been accepted in the clinic, and the development of materials has led to more refined extraction instruments. Meanwhile the use of micro-power devices has greatly improved the efficiency of tooth extraction. Advancements in tooth extraction techniques and equipments are aimed to maximumly preserve the integrity of the alveolar bone, reduce the complications, and relieve the pain. This paper described the development of minimally invasive tooth extraction techniques through the evolution of instruments and the application of micro-power devices, so as to provide reference for more dentists to understand and apply minimally invasive equipments in daily practice.
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    Preliminary application of domestic robotic system in oral and maxillofacial surgery
    SUN Qing, XIANG Xi-ting, MA Chao, WU Li-meng, SUN Xi-kun, ZHANG Tao
    China Journal of Oral and Maxillofacial Surgery    2025, 23 (1): 13-19.   DOI: 10.19438/j.cjoms.2025.01.003
    Abstract1134)      PDF (1093KB)(460)      
    PURPOSE: To explore the application effect of domestic robot system in oral and maxillofacial surgery, and to provide reference for the application of robot-assisted technology in the resection and reconstruction of oropharyngeal and facial-neck tumors. METHODS: Eighteen patients underwent surgeries assisted by KangDuo Surgical System at the Department of Oral and Maxillofacial Surgery, Peking Union Medical College Hospital, between November 2023 and June 2024. These cases comprised 13 oropharyngeal tumors, three facial neck tumors, and a pair of latissimus dorsi myocutaneous flap procedures. Operation duration, robot operating time,hospitalization periods, postoperative complications, facial aesthetics, facial perioral edema, temporomandibular joint discomfort, and other parameters were analyzed statistically. RESULTS: All operations were successfully completed using the robotic system without requiring conversion to traditional open surgery. The mean operation time using the robotic assistance reached (123.1±85.8) min with a mean total operation time of (333.7±250.2) min. The average postoperative stay in the hospital was recorded as (5.89±4.56) days. In the management of oropharyngeal tumors, 9 patients underwent tumor resections while 4 patients received biopsies. Four cases simultaneously underwent local flap transplantation, and 2 cases received forearm free flap transplants concurrently. All patients with oropharyngeal tumors demonstrated satisfactory recovery following surgical procedures, with no delayed bleeding reported. A 100% survival rate was noted for all flaps utilized, and postoperative pathological examinations revealed no positive surgical margins. After extubation, all patients could eat normally without experiencing significant coughing episodes, tracheotomy tubes were removed according to schedule. A dislocation of the temporomandibular joint was observed in one patient during the procedure, which subsequently improved following manual reduction. Additionally, one patient developed a hematoma at this site on the second postoperative day after submandibular gland surgery. No other complications were reported. Two patients experienced mild throat discomfort a month after their surgeries, yet no obvious discomfort was seen among other patients. All patients had no discomfort 3 months after surgery, and all were satisfied with the appearance during the follow-up period. CONCLUSIONS: The KangDuo robot system has yielded satisfactory outcomes within oral and maxillofacial surgery especially inducing less surgical trauma and enhancing patient quality of life. Future advancement should focus on improving equipment precision applicability and inventing specialized tools dedicated to oral and maxillofacial surgeries to address complex maxillofacial procedures.
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    Expert consensus on surgical treatment of hemangiomas and vascular malformations in the head and neck
    WANG Yan-an, QIN Zhong-ping, ZHENG Jia-wei, LI Chun-jie, LIU Shao-hua, YANG Yao-wu, CHEN Gang, CHEN Wei-liang, LIU Xue-jian, DU Zhong, ZHANG Lei, WANG Ye-fei, WANG De-ming, SU Li-xin, XIE Feng, DONG Chang-xian, GUO Lei, LI Kai, GU Song, HE Yue, ZHANG Zhi-yuan
    China Journal of Oral and Maxillofacial Surgery    2024, 22 (2): 105-117.   DOI: 10.19438/j.cjoms.2024.02.001
    Abstract1132)      PDF (2515KB)(803)      
    Hemangiomas and vascular malformations are common benign vascular diseases in the head and neck region. The evolution and extensive implementation of non-surgical therapeutic modalities have resulted in considerable improvement or even total remission in a significant number of patients in minimally invasive or non-invasive procedures. Nonetheless, under certain circumstances, surgical treatment remains an irreplaceable treatment modality within the comprehensive treatment sequence for hemangiomas and vascular malformations in the head and neck. However, there is no established standard or consensus in the academic community on how to choose and apply surgical treatment. Therefore, to enhance the treatment efficacy of hemangiomas and vascular malformations amongst domestic peers, and to standardize surgical treatment protocols, this consensus brings together the discussion opinions of relevant experts from many medical schools and affiliated hospitals nationwide. Based on the latest domestic and international research results and diagnosis and treatment experience, we formulated this expert consensus from the aspects of preoperative diagnosis and preparation, surgical treatment indications and strategies, postoperative care and observation, common complications and treatment after surgery, follow-up and social psychological support. It is expected to be used in clinical practice and to guide relevant professional doctors carrying out treatment.
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    Progress in the application of artificial intelligence in the early diagnosis of oral cancer
    ZHAO An-yuzhuo, SHI Xing-lian, LIU Huan, JIANG Jian-hong, LI Zhe-zhen, LIU Mei
    China Journal of Oral and Maxillofacial Surgery    2024, 22 (5): 493-498.   DOI: 10.19438/j.cjoms.2024.05.014
    Abstract925)      PDF (831KB)(660)      
    The early diagnosis of cancer is conducive to the subsequent clinical management of patients. Artificial intelligenceAI has been widely used in the medical field, improving the accuracy and efficiency of disease diagnosis. This paper summarized the relevant studies on AI in the diagnosis and screening of oral cancer from three aspects: overview of AI in the early diagnosis of oral cancer, application status of commonly used AI types, and personal outlook, aiming to provide a new perspective for the application of early diagnosis of oral cancer, further help medical workers improve medical decision-making rate, and provide references for the early diagnosis and treatment of oral cancer.
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    Recent advances in mouth breathing diagnosis and effects on dento-maxillofacial development in children
    ZHENG Yang-shan, YUAN Xue-shun, JIANG Jing, QIU Shu-qi, SHI Zhao-hui
    China Journal of Oral and Maxillofacial Surgery    2024, 22 (1): 92-101.   DOI: 10.19438/j.cjoms.2024.01.016
    Abstract918)      PDF (1261KB)(790)      
    Upper airway obstruction can lead to mouth breathing, which is much prevalent in children. Studies have indicated that in early childhood, prolonged mouth breathing leads to muscular and postural alterations which, in turn, result in dentoskeletal changes, or even worse, dentofacial deformities and sleep-related breathing disorders. A multidisciplinary team, involving otolaryngologists, dental providers, and somnologists, should work to provide early diagnosis and appropriate treatment, preventing the consequent disorders of mouth breathing. More and more studies in recent years have focused on mouth breathing diagnosis and its effects on dento-maxillofacial development as well as its possible mechanisms in children. Nevertheless, the etiology, diagnosis, treatment options, postoperative care, mechanism of mouth breathing impact on dento-maxillofacial development, and its relationship with sleep-disordered breathing remain controversial. This review summarized the latest advances in mouth breathing, demonstrating the current status and advances of research on mouth breathing diagnosis, dento-maxillofacial development, and multidisciplinary collaboration.
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    Effect of columnar collagen sponge on the extraction of impacted teeth and the risk of complications
    WANG Chen-xin, PENG Jing, HUANG Xin, SHI Le, DAI Xiao-feng
    China Journal of Oral and Maxillofacial Surgery    2023, 21 (2): 146-151.   DOI: 10.19438/j.cjoms.2023.02.008
    Abstract901)      PDF (963KB)(488)      
    PURPOSE: To investigate the effect of collagen sponge in the extraction of impacted teeth and the risk of complications. METHODS: A total of 160 patients with impacted teeth extraction were selected from June 2021 to December 2021 in Shanghai Jing'an Dental Clinic. The patients were randomly divided into experimental group and control group, 80 cases in each group. Both groups underwent conventional extraction of impacted teeth, and the control group was rinsed with 20 mL sodium chloride solution after extraction. In the experimental group, on the basis of the control group, columnar collagen sponge was inserted into the extraction wound. Bleeding, postoperative pain score, postoperative swelling degree 7 days after surgery, levels of inflammatory factors[prostaglandin E2(PGE2), myeloperoxidase(MPO), calcitonin gene-related peptide(CGRP)] in gingival crevicular fluid before and after treatment and postoperative complications (restricted opening, inflammatory induration or bruising of maxillofacial region, infection, dry socket) were compared between the two groups. SPSS 22.0 software package was used for data analysis. RESULTS: The postoperative bleeding time of the experimental group was significantly lower than that of the control group(P<0.05). The VAS scores of spontaneous pain and dysphagia in the experimental group were significantly lower than those of the control group(P<0.05). The swelling degree of experimental group was significantly lower than that of control group 7 days after tooth extraction(P<0.05). There was no difference in PGE2, MPO and CGRP between the two groups before treatment(P>0.05). After treatment, PGE2, MPO and CGRP in the two groups were significantly increased(P<0.05), PGE2, MPO and CGRP of the experimental group after treatment were significantly lower than those of the control group after treatment(P<0.05). The incidence of postoperative complications in the experimental group was significantly lower than that in the control group (P<0.05). CONCLUSIONS: Columnar collagen sponge has a good effect in extraction of impacted teeth, and can effectively avoid postoperative complications, and has little influence on inflammatory factors in gingival crevicular fluid, which is worthy of wide application.
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    Visual analysis of clinical research literatures on temporomandibular joint disorders at both home and abroad from 2013 to 2023
    LIU Xing-yu, JIANG Nan
    China Journal of Oral and Maxillofacial Surgery    2025, 23 (2): 185-195.   DOI: 10.19438/j.cjoms.2025.02.014
    Abstract849)      PDF (2071KB)(862)      
    PURPOSE: To analyze the evolution of domestic and international clinical researches on temporomandibular joint disorders(TMD) from 2013 to 2023,to understand the development trends and research hotspots, and to explore future research directions. METHODS: Clinical research literatures on TMD published between 2013 and 2023 were collected through PubMed, China National Knowledge Infrastructure(CNKI), Wanfang Data, and VIP databases. CiteSpace 6.1.R6 software was utilized for visual analysis. Methods included keyword frequency statistics, co-occurrence analysis, clustering analysis, and timeline analysis to construct knowledge maps and identify research hotspots. RESULTS: Domestic research hotspots were primarily focused on pain management, acupuncture therapy, and tissue repair. In contrast, international researches heavily emphasized quality of life and non-invasive treatment approaches. Both domestic and international studies underscored the importance of interdisciplinary integration and the application of new technologies. Keywords such as "acupuncture treatment" have appeared relatively late in domestic researches but showed a clear trend, indicating an interest in the application of traditional medicine and emerging technologies. International researches had earlier focused on psychological factors and quality of life, and leaded in the application of new materials and technologies. CONCLUSIONS: Although there are differences in methods and focal points between domestic and international researches, there is a consistent focus on core issues such as pain management and the application of imaging technologies. Future researches should enhance attention to psychological factors and comprehensive health management, draw on international experience, explore the application of new materials and new technologies, and promote interdisciplinary collaboration to improve the diagnosis and treatment of temporomandibular joint disorders and the quality of life of patients.
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    Single-cell transcription atlas for mandibular condyle cartilage and subchondral bone marrow in rat temporomandibular joint osteoarthritis
    YU Ye-ke, DING Ruo-yi, SUN Jia-li, ZHANG Zhi-yuan, HE Dong-mei
    China Journal of Oral and Maxillofacial Surgery    2023, 21 (4): 332-339.   DOI: 10.19438/j.cjoms.2023.04.003
    Abstract800)      PDF (2829KB)(782)      
    PURPOSE: To establish the single-cell transcriptome atlas for rat condyle osteochondral tissue and bone marrow both in normal and temporomandibular joint osteoarthritis (TMJOA) condition. METHODS: Rat unilateral anterior crossbite(UAC) model was built to induce TMJOA. Osteochondral cells and bone marrow immune cells were extracted for single-cell RNA sequencing. Quality control, dimension reducing, clustering and marker gene detection were used to depict cell subclusters. Differential gene expression analysis and functional enrichment were utilized to demonstrate cell cluster functions and their changes under UAC. Pseudo-time analysis was applied for cell development trajectory, while cell communication prediction was used to show alternations in the interaction among cell clusters. RESULTS: There were 9 cell clusters in rat condyle, containing osteochondral cells and bone marrow immune cells. Under UAC, the number of osteochondrocytes decreased whereas immune cells accumulated. Condyle cartilage and bone tissue contained 6 functional groups of cells. Among them, D and F group maintained progenitor characteristics and possessed the ability to develop into other groups. In UAC condition, osteochondrocytes witnessed impaired extracellular matrix organization, activated senescent or inflammatory pathways, and diminished cell-cell interaction. Meanwhile, in the bone marrow, neutrophils showed enhanced chemotaxis and degranulation, mononuclear-phagocytes displayed increased phagosomes, activated B cells were also recruited. CONCLUSIONS: There are progenitor cells in condyle cartilage and bone tissue, whose function impaired under UAC. At the same time, immune cells in the bone marrow are activated. Targeted modulation of osteochondral progenitors and immune cells could contribute in alleviation the condyle tissue damage in TMJOA.
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    Effectiveness of augmented corticotomy assisted orthodontics in 35 adult patients with moderate to severe periodontitis
    GUO Qiu-man, YU Hong-bo, XIA Yun-hui, WANG Bo
    China Journal of Oral and Maxillofacial Surgery    2024, 22 (6): 553-557.   DOI: 10.19438/j.cjoms.2024.06.006
    Abstract787)      PDF (1225KB)(247)      
    PURPOSE: To quantitatively evaluate the effect of augmented corticotomy assisted orthodontics in adult patients with moderate to severe periodontitis. METHODS: The sample comprised 102 mandibular incisors of 35 adult patients with moderate to severe periodontitis in mandibular anterior region who accepted augmented corticotomy assisted orthodontic treatment selected from consecutive patients at the Department of Oral and Craniomaxillofacial Surgery, Shanghai Ninth People's Hospital since Jan.2017. Periodontal soft and hard tissue measurements were appraised with the help of periodontal clinical assessment and cone-beam CT(CBCT) examination at different time points. SAS 9.1 software package was used for data analysis. RESULTS: Facial appearance aesthetics, fine occlusal relationships, and effectively controlled periodontal inflammation were realized for all patients after treatment; moderate to severe, favorable bone augmentation on the labial side at root apex level was achieved with minimal root resorption, bone thickness on the labial side at 1/2 and 3/4 root length level was maintained as well as vertical alveolar bone level on both labial and lingual sides. CONCLUSIONS: Augmented corticotomy assisted orthodontics is a promising approach for the treatment of adult patients with moderate to severe periodontitis.
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    Evaluation of the application of double wire anchor nails in temporomandibular joint disc anchorage
    WUERGULI Alifu, REYILAI Abudukeremu, LIU Jiang-long, MAIMAITITUXUN Tuerdi
    China Journal of Oral and Maxillofacial Surgery    2023, 21 (4): 397-402.   DOI: 10.19438/j.cjoms.2023.04.013
    Abstract781)      PDF (1789KB)(562)      
    PURPOSE: To evaluate the clinical efficacy of double wire anchorage in the treatment of temporomandibular joint disc anterior displacement. METHODS: Thirty patients with anterior disc displacement without reduction(ADDWoR) diagnosed in First Affiliated Hospital of Xinjiang Medical University from June 2021 to February 2022 were included to fix the discs with double wire anchors. The maximal open mouth, visual analogue scale (VAS) scores of the patients before and at different time periods were analyzed, the patients' self-satisfaction was recorded, and the length of MRI discs and condylar height before and after operation were measured. SPSS 25.0 software was used to analyze the data and evaluate the surgical results. RESULTS: The mean age was 24.43±8.87 years old, the mean mouth opening before operation was (29.17±5.38) mm (19-42 mm), the mean maximum mouth opening after operation was (39.17±2.57) mm (35-45 mm), and 93.3% of the patients after operation had the maximum mouth opening >35 mm; the mean VAS before operation was 58.33±21.19 (10-90), the mean VAS 6 months after operation was 11.67±6.99(0-20), the mouth opening and the value of VAS 6 months after operation had significant difference compared with prior to operation(P<0.05). The disc length was (9.77±0.63), (11.96±0.68) and (12.72±0.55) mm preoperatively, immediately postoperatively and 6 months after surgery. The condyle height increased by (1.08±0.61) mm 6 months after surgery compared with immediately postoperatively (P<0.05). CONCLUSIONS: Double wire anchorage in the reduction and anchorage of TMJ disc can improve the mouth opening, relieve pain, increase the length of TMJ disc and increase the height of condyle.
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    Analysis of highly cited papers in Chinese core journals of stomatology from 2016 to 2021
    LI Xue-lu, XU Ling, ZHANG Hui-hong
    China Journal of Oral and Maxillofacial Surgery    2023, 21 (3): 272-278.   DOI: 10.19438/j.cjoms.2023.03.012
    Abstract750)      PDF (1055KB)(306)      
    PURPOSE: To objectively evaluate the distribution characteristics of highly cited papers(HCP) in 19 core journals of stomatology, and to explore the recent research hotspots in stomatology. METHODS: HCPs in 19 core journals of stomatology from January 2016 to December 2021were retrieved from CNKI database. The years, institutions, journals, fund, key words and the citation frequencies of HCPs were recorded. The data were analyzed by bibliometrics methods and SATI was used to draw a co-occurrence knowledge map. RESULTS: A total of 187 highly cited papers was selected. “Chinese Journal of Stomatology” was the journal with the most HCPs and the highest total citations, while “Shanghai Journal of Stomatology” with the highest mean citation counts. The top 10 institutions published 99 HCPs, accounting for 52.94%. The largest number of HCPs had a collaboration among 2 authors. There were 96 papers supported by fund (51.34%) while 91 papers without fund(48.66%). Among the six highest cited papers in the years, 3 were editorials, 2 were consensus and guidelines, and 1 was clinical research. "Chronic periodontitis", "root canal treatment", "CAD/CAM" and "clear aligners" were the most common key words. CONCLUSIONS: There is a mutual relationship between establishing a good journal brand and high-quality papers. The best cooperation scale should be selected for scientific creation. Editorials, consensus and guidelines in stomatology have an obvious advantage in achieving high citations. "Digital stomatology" may be the development trend and frontier in the next few years. The research results have certain guidance value for the construction of journals, manuscript selection and talent training.
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    Chinese expert consensus on prevention and management of perioperative venous thromboembolism in head and neck cancer patients
    REN Zhen-hu, CHEN Ming-tao, WU Han-jiang, ZHANG Sheng, FANG Kun, XIE Shang4, LIU Yu, HU Chuan-yu6, LIU Bing, LI Chun-Jie, ZHU Gui-quan, WANG Cheng, GAO Yang, ZHANG Xiao-chen, SHI Jian-bo, ZHANG Yong-hong, CUI Ming-zhe, JI Tong, REN Guo-xin, WANG Yan-an, CHEN Wei-liang, ZHANG Chen-ping, HE Yue, ZHANG Zhi-yuan
    China Journal of Oral and Maxillofacial Surgery    2024, 22 (1): 1-9.   DOI: 10.19438/j.cjoms.2024.01.001
    Abstract737)      PDF (1276KB)(704)      
    Venous thromboembolism (VTE) is a common complication after surgical procedures, and an important risk factor for unexpected death in hospitals, and the second leading cause of death for tumor patients. Patients with advanced head and neck cancer usually require extensive radical surgery and simultaneous repair and reconstruction surgery, and have many risk factors such as elderly, long surgical time, long postoperative bed rest, and hypercoagulable state caused by tumor and chemotherapy drugs, which suggest that patients with head and neck cancer should be an extremely high risk group for VTE. However, little attention has been paid to the occurrence of VTE in patients with cancer in the head and neck, and the data on the incidence of VTE after head and neck cancer surgery are also limited. So far, there is a lack of relevant treatment consensus or guidelines for perioperative VTE of head and neck cancer in China. The level of prevention and management of perioperative VTE of head and neck cancer varies among different institutions, and there is a lack of unified and scientific diagnosis and treatment standards and objective evaluation system for prevention and management. In order to unify and standardize the diagnosis and treatment of perioperative VTE in head and neck cancer, reduce the waste of medical resources and improve the treatment effectiveness, domestic experts in this field have repeatedly discussed the diagnosis and treatment opinions from 14 famous medical institutions in China. This article refers to the research results and diagnosis and treatment experience of perioperative VTE in head and neck cancer world wide in recent years, and formulates this expert consensus for reference by relevant clinicians.
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    Research progress in the role and mechanism of Porphyromonas gingivalis in promoting oral squamous cell carcinoma
    REZIWANGULI·Yasen, MAIREPATI·Maiming, LI Chen-xi, GONG Zhong-cheng
    China Journal of Oral and Maxillofacial Surgery    2023, 21 (2): 186-190.   DOI: 10.19438/j.cjoms.2023.02.015
    Abstract690)      PDF (550KB)(381)      
    A large number of studies have shown that P.gingivalis is one of the bacterial species, as an important risk factor, of oral squamous cell carcinoma (OSCC). P.gingivalis is closely associated with the pathogenicity, development, invasion, metastasis and prognosis of OSCC. For its potential mechanisms, it may accelerate OSCC occurrence and progress probably through multiple ways as follows: resisting and destroying the innate immune system of the host, promoting epithelial-mesenchymal transition, promoting cancerous invasion and metastasis, inhibiting cell apoptosis, activating cell proliferation. This review summarized the research progress in the role and mechanism of P.gingivalis in promoting OSCC.
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    Modified paranasal bone grafting reduced vertical maxillary recurrence after Le Fort Ⅰ osteotomy
    GE Wei-wen, QI Lei, WANG Yun, ZHANG Lei
    China Journal of Oral and Maxillofacial Surgery    2023, 21 (2): 163-167.   DOI: 10.19438/j.cjoms.2023.02.011
    Abstract689)      PDF (1049KB)(261)      
    PURPOSE: To evaluate if the modified paranasal bone grafting can reduce the recurrence of Le Fort I osteotomy for maxillary downward. METHODS: A total of 30 patients with a large maxillary downward movement (>3 mm) during orthognathic surgery were included in the study. Patients were divided into modified paranasal bone grafting group and non-modified paranasal bone grafting group. Three-dimensional measurements of the maxillary position were taken using maxillofacial CT data at preoperative(T0), 3 days postoperatively(T1), and 6 months postoperatively (T2). Meanwhile, CT scans of T1 and T2 were used to calculate the changes in bone thickness. SPSS 22.0 software package was used for data analysis. RESULTS: At 6 months after operation, in the vertical direction, the recurrence amount of U1 in the modified paranasal bone grafting group was (0.54±0.35)mm, and the recurrence amount of U1 in the non-modified paranasal bone grafting group was (1.18±0.76)mm(P=0.3997). There was no significant difference in recurrence between the two groups in the anteroposterior and horizontal directions. In the modified group, the bone graft thickness was reduced by (11.75±6.25)%, and that of the non-modified group was (33.77±11.56)%(P<0.0001). CONCLUSIONS: Modified nasal bone graft can effectively reduce the absorption of bone graft and decrease the vertical recurrence of maxilla.
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    Current status of maxillary sinus floor augmentation technology
    CHEN Jun, XU Guang-zhou
    China Journal of Oral and Maxillofacial Surgery    2023, 21 (3): 291-300.   DOI: 10.19438/j.cjoms.2023.03.015
    Abstract667)      PDF (843KB)(430)      
    Tooth loss in the maxillary posterior region often leads to the lack of vertical bone mass between the maxillary sinus floor and the alveolar crest in the missing region. Maxillary sinus floor augmentation is the mainstream method to solve vertical bone mass deficiency in the posterior maxillary region. Since the 1960s, from origin to develop until maturity, the research of maxillary sinus floor augmentation has been continuously innovated. This article reviewed the evolution, common complications and management of maxillary sinus floor augmentation, bone grafting, pathological changes and management of maxillary sinus, and the influence of anatomic factors of maxillary sinus on osteogenesis.
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    Application and efficacy evaluation of functional fixator in the fenestration treatment of jaw cyst
    ZHOU Yun, WANG Zhen, ZHAO Xiao-mei
    China Journal of Oral and Maxillofacial Surgery    2023, 21 (3): 263-266.   DOI: 10.19438/j.cjoms.2023.03.010
    Abstract666)      PDF (794KB)(429)      
    PURPOSE: To evaluate the effect of functional occlusal device in the fenestration of jaw cyst. METHODS: Fifty patients with jaw cyst who underwent fenestration surgery for the first time were selected. According to the treatment methods, they were divided into the conventional treatment group and functional treatment group, with 25 cases in each group. Obturator functioning scale (OFS) was used to evaluate the comfort, masticatory efficiency and aesthetics of patients wearing two kinds of different endodontics during fenestration treatment. The patients' satisfaction with the final restoration was investigated by questionnaire. SPSS 20.0 software package was used for data analysis. RESULTS: Compared to conventional obturators, the functional obturator group showed a statistically significant reduction in mandibular and maxillary tooth extension after healing of the lesion (P<0.01). However, there was no significant difference in chewing efficiency during the wearing of the obturator(P>0.05). The esthetic satisfaction of the functional obturator was significantly higher in patients with anterior tooth loss(P<0.01). CONCLUSIONS: The functional obturator, which combines the functions of denture restoration, not only has good esthetics and wearing comfort, but also better maintains stability in missing interdental spaces and is more favorable for the restoration of missing teeth.
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    lymphatic-venous anastomosis for head and neck lymphedema using supermicrosurgery: case report and literature review
    REN Zhen-hu, GU Shi-lin, JI Tong, HE Yue, ZHANG Zhi-yuan, ZHENG You-mao
    China Journal of Oral and Maxillofacial Surgery    2023, 21 (3): 306-308.   DOI: 10.19438/j.cjoms.2023.03.017
    Abstract657)      PDF (958KB)(498)      
    In recent years, surgical treatment of limbs and trunk lymphedema has gradually attracted attention, but little is paid to head and neck lymphedema. In this paper, we reported a case of lymphedema of head and neck treated by super microsurgery with lymphatic-venous anastomosis(LVA), and discuss its pathogenesis, clinical manifestations, diagnosis and treatment based on relevant literature.
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