Tongue squamous cell carcinoma, oropharyngeal carcinoma and gingival carcinoma secondary to nasopharyngeal carcinoma: a case report and literature review

doi:10.19438/j.cjoms.2023.03.016

Abstract

Abstract: Nasopharyngeal carcinoma (NPC) is a relatively rare disease in the world, with a unique geographical distribution, but high incidence in Southeast Asia. Nasopharyngeal carcinoma is mostly poorly differentiated squamous cell carcinoma (98%) and radiotherapy is the first choice of treatment. Radiotherapy and chemotherapy have been considered to have a duality, which can treat cancer and cause cancer. The probability of radionecrosis of the jaw after radiotherapy for head and neck cancer is 1%-3%, mainly occurring in the mandible. This paper reported a case of left tongue squamous cell carcinoma, left oropharyngeal carcinoma and left lower gingival carcinoma after radiotherapy and chemotherapy for nasopharyngeal carcinoma, and the occurrence of radiation osteomyelitis of the jaw. The history, clinical manifestations, treatment and prognosis of this case were discussed based on reviewing the literature.

Key words: Nasopharyngeal carcinoma, Radiotherapy, Tongue squamous cell carcinoma, Carcinoma of the oropharynx, Carcinoma of the gingiva, Osteoradionecrosis of the jaw

CLC Number:

R739.8

WANG Bo, SHEN Yue-hong, YANG Hong-yu. Tongue squamous cell carcinoma, oropharyngeal carcinoma and gingival carcinoma secondary to nasopharyngeal carcinoma: a case report and literature review[J]. China Journal of Oral and Maxillofacial Surgery, 2023, 21(3): 301-305.

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