China Journal of Oral and Maxillofacial Surgery ›› 2024, Vol. 22 ›› Issue (4): 404-408.doi: 10.19438/j.cjoms.2024.04.015

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Diagnosis and treatment of head and neck sarcoma

GUO Yi-fei1, ZHANG Yong-hong1, REN Zhen-hu2   

  1. 1. Department of Stomatology, Huaihe Hospital of Henan University. Kaifeng 475000, Henan Province;
    2. Department of Oromaxillofacial Head and Neck Oncology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine; College of Stomatology, Shanghai Jiao Tong University; National Center for Stomatology; National Clinical Research Center of Oral Disease; Shanghai Key laboratory of Stomatology; Shanghai Research Institute of Stomatology. Shanghai 200011, China
  • Received:2023-11-02 Revised:2024-01-06 Online:2024-07-20 Published:2024-08-07

Abstract: Sarcoma is a low-occurrence malignant tumor,head and neck sarcoma has a lower incidence rate. Due to the low probability of sarcoma and the lack of obvious early clinical symptoms, it is difficult to diagnose before treatment. Diagnosis needs to integrate clinical symptoms and imaging, pathological findings, and tumor markers, etc. At present, the key technical point for treatment of sarcoma is still wide margin surgery. Chemotherapy, radiotherapy, targeted and immunotherapy can enhance the treatment effect or improve the prognosis. Advances in research on new biomarkers and photodynamic therapy can provide more ways for the diagnosis and treatment of sarcomas in the future. The purpose of this article is to briefly describe the current mainstream diagnosis and treatment methods for head and neck sarcomas and prospects for future diagnosis and treatment.

Key words: Head and neck sarcoma, Diagnosis, Biomarkers, Surgical treatment, Adjuvant radiotherapy and chemotherapy

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