Meta-analysis of risk factors associated with postoperative delirium after head and neck surgery

Abstract

Abstract: PURPOSE: To explore the risk factors associated with postoperative delirium after head and neck surgery. METHODS: A systematic search of MEDLINE, Cochrane Library, EMBASE, ISI Web of Knowledge, Google scholar, CNKI, WanFang, VIP databases, up to January 2014, was performed to identify articles about risk factors for postoperative delirium after head and neck surgery. Meta-analysis was performed by RevMan5.2. RESULTS: Seven studies regarding the risk factors associated with postoperative delirium after head and neck surgery were collected, involving 1664 cases in total, two hundred thirty-seven cases in delirium group and 1427 cases in non-delirium group. Meta-analysis showed that age (WMD:5.70, 95% CI:1.96-9.43, P<0.001), gender (OR:1.51, 95% CI:1.07-2.12, P<0.05), solitude (OR:2.22, 95% CI:1.42-3.48, P<0.001), preoperative mental disease (OR:2.57, 95% CI:1.60-4.15, P<0.05), alcohol abuse (OR:1.74, 95% CI:1.79-2.54, P<0.05) and time of operation and anesthesia (WMD:63.93, 95% CI:9.47-118.38, P<0.05) were related to postoperative delirium after head and neck surgery. There was no significant difference in radical neck dissection, free flap reconstruction, tracheotomy and restriction of mobility between patients with and without postoperative delirium (P>0.05). CONCLUSIONS: Age, gender, solitude, preoperative mental disease, alcohol abuse and time of operation and anesthesia are risk factors for postoperative delirium after head and neck surgery.

Key words: Delirium, Risk factors, Head and neck surgery, Meta analysis

CLC Number:

R782.05.4

CHEN Jia-wei, HUANG Yan, XU Hui, JIANG Hong. Meta-analysis of risk factors associated with postoperative delirium after head and neck surgery[J]. China Journal of Oral and Maxillofacial Surgery, 2015, 13(2): 175-181.

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