Effect of early rehabilitation training in patients with oral cancer after free flap reconstruction: a meta-analysis

doi:10.19438/j.cjoms.2020.02.017

Abstract

Abstract: PURPOSE： To evaluate the effect of early systematic rehabilitation training on oral cancer patients after radical resection with free flap to repair soft tissue defects. METHODS: Randomized controlled trials (RCTs) on the effects of early rehabilitation training on function recovery of patients with oral cancer in China and aboard were retrieved from the Cochrane Library, Web of Science, PubMed, Embase, China National Knowledge Infrastructure, VIP Citation Database, and WanFang Data. Review Manager 5.3 software was used to perform meta analysis. RESULTS: A total of 12 eligible literatures were included. Meta analysis showed that the swallowing function score in the experimental group was significantly lower than that of the control group 2 weeks after surgery[SMD=-1.22, 95%CI(-1.55,-0.90), Z=7.41, P<0.001]. The excellent and good rate of speech intelligibility of the patients in the experimental group was significantly higher than that in the control group [RR=1.44, 95%CI(1.16,1.78), Z=3.33, P<0.001]. The speech intelligibility score in the experimental group was significantly higher than those in the control group 3 and 6 months after surgery[MD=13.01, 95%CI(6.78,19.24), Z=4.09, P<0.001;MD=7.90, 95%CI(3.19,12.61), Z=3.29, P<0.01]. CONCLUSIONS: Early rehabilitation training is helpful to recovery of swallowing function and speech function in patients with oral cancer after free flap repair.

Key words: Oral cancer, Rehabilitation, Function training, Swallowing function, Speech intelligibility, Meta analysis

CLC Number:

R782.2

YE Hai-chun, GAO Xian-lian, REN Yang, LI Li. Effect of early rehabilitation training in patients with oral cancer after free flap reconstruction: a meta-analysis[J]. China Journal of Oral and Maxillofacial Surgery, 2020, 18(2): 171-176.

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