Research progress of β-catenin in tooth development

doi:10.19438/j.cjoms.2023.04.016

Abstract

Abstract: β-catenin is the central hub in the canonical Wnt/β-catenin signaling pathway, which plays an important role in the regulation of odontogenesis and tooth development. In this paper, we reviewed the recent research progress in terms of the expression pattern of β-catenin during tooth development, the molecular mechanism of β-catenin in tooth development process which includes odontogenesis, crown development and root formation. It may provide a reference for elucidation of tooth development mechanism, exploration of potential therapeutic targets of tooth development related diseases, and precise regulation of tooth regeneration.

Key words: β-catenin, Wnt/β-catenin signaling pathway, Tooth development, Root formation

CLC Number:

SUI Xin, DU Zhong. Research progress of β-catenin in tooth development[J]. China Journal of Oral and Maxillofacial Surgery, 2023, 21(4): 413-417.

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