Abstract: PURPOSE: To evaluate the usefulness and clinical outcomes of reconstruction of maxillary class Ⅲ defect using 3-D computer-assisted fabricated individual titanium mesh technique. METHODS: This retrospective study included 6 patients with maxillary class Ⅲ defect after total maxillectomy performed from May 2014 to August 2015. A 3-dimensional individualized stereo maxillary model based on mirror images of the unaffected maxilla was obtained to fabricate an anatomically adapted titanium mesh using computer-assisted design and manufacturing. The individual titanium mesh was inserted into the maxillary class Ⅲ defect after total maxillectomy. The incidence of postoperative complications was evaluated and the postoperative globe projection and orbital volume were measured. SPSS 17.0 software package was used for statistical analysis. RESULTS: All patients were satisfied with their postoperative facial symmetry and did not develop diplopia or endophthalmos. The postoperative orbital volume was 26.53±0.73 mL on the affected side and 26.63±0.66 mL on the unaffected side (P=0.65), and the globe projection was 16.15±0.37 mm and 16.67±0.65 mm, respectively (P=0.07). Titanium mesh exposure was observed in 1 patient and mild limitation of mouth opening was observed in 2 patients who underwent postoperative radiotherapy. CONCLUSIONS: Reconstruction of maxillary class Ⅲ defect with individual titanium mesh fabricated using computer-assisted techniques can achieve successful clinical outcomes, preserving orbital volume and globe projection.

Key words: 3-dimensional printing, Titanium mesh, Maxillary defect