牙源性角化囊肿诊疗中国专家共识

doi:10.19438/j.cjoms.2022.03.001

中国口腔颌面外科杂志 ›› 2022, Vol. 20 ›› Issue (3): 209-218.doi: 10.19438/j.cjoms.2022.03.001

牙源性角化囊肿诊疗中国专家共识

刘冰^1#, 何悦^2#, 彭歆³, 孙长伏⁴, 韩正学⁵, 吴煜农⁶, 彭利伟⁷, 赵熠⁸, 陶谦⁹, 韩新光¹⁰, 李劲松¹¹, 苏彤¹², 李波¹³, 张雷³, 胡砚平¹⁴, 陈传俊¹⁵, 李一¹⁶, 李铁军^17,*, 赵怡芳^1,*

1.武汉大学口腔医院口腔颌面-头颈肿瘤外科,湖北武汉 430070;
2.上海交通大学医学院附属第九人民医院口腔颌面-头颈肿瘤科,上海 200011;
3.北京大学口腔医学院口腔颌面外科,北京 100081;
4.中国医科大学附属口腔医院口腔颌面-头颈外科,辽宁沈阳 110002;
5.首都医科大学附属北京口腔医院口腔颌面-头颈肿瘤科,北京 100050;
6.南京医科大学附属口腔医院口腔颌面外科,江苏南京 210029;
7.郑州大学河南省人民医院口腔医学中心,河南郑州 450000;
8.武汉大学口腔医院口腔修复科,湖北武汉 430070;
9.中山大学光华口腔医学院附属口腔医院口腔颌面外科,广东广州 510055;
10.郑州大学附属第一医院口腔颌面外科,河南郑州 450052;
11.中山大学孙逸仙纪念医院口腔颌面外科,广东广州510120;
12.中南大学湘雅医院口腔颌面外科,湖南长沙 410008;
13.武汉大学口腔医院放射科,湖北武汉 430070;
14.厦门医学院附属口腔医院口腔颌面外科,福建厦门 361006;
15.中国科学技术大学附属第一医院口腔颌面外科,安徽合肥 230001;
16.四川大学华西口腔医院头颈肿瘤外科,四川成都 610041;
17.北京大学口腔医学院口腔病理科,北京 100081

收稿日期:2022-03-14 修回日期:2022-03-26 出版日期:2022-05-20 发布日期:2022-05-20
通讯作者: 李铁军,E-mail: litiejun22@vip.sina.com;赵怡芳,E-mail: yifang@whu.edu.cn。^*共同通信作者
作者简介:刘冰（1968-）,男,博士,主任医师,E-mail: liubing9909@whu.edu.cn;何悦（1973-）,男,博士,教授、主任医师,E-mail: william5218@126.com。^#并列第一作者

Chinese Expert consensus on the diagnosis, treatment of odontogenic keratocyst

LIU Bing¹, HE Yue², PENG Xin³, SUN Chang-fu⁴, HAN Zheng-xue⁵, WU Yu-nong⁶, PENG Li-wei⁷, ZHAO Yi⁸, TAO Qian⁹, HAN Xin-guang¹⁰, LI Jin-song¹¹, SU Tong¹², LI Bo¹³, ZHANG Lei³, HU Yan-ping¹⁴, CHEN Chuan-jun¹⁵, LI Yi¹⁶, LI Tie-jun¹⁷, ZHAO Yi-fang¹

1. Department of Oromaxillofacial Head and Neck Oncology, Hospital of Stomatology, Wuhan University. Wuhan 430070, Hubei Province;
2. Department of Oromaxillofacial Head and Neck Oncology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine. Shanghai 200011;
3. Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology. Beijing 100081;
4. Department of Oromaxillofacial Head and Neck Surgery, School and Hospital of Stomatology, China Medical University. Shenyang 110002, Liaoning Province;
5. Department of Oral and Maxillofacial Head and Neck Oncology, Beijing Stomatological Hospital, Capital Medical University. Beijing 100050;
6. Department of Oral and Maxillofacial Surgery, Stomatological Hospital Affiliated to Nanjing Medical University. Nanjing 210029, Jiangsu Province;
7. Department of Stomatology, Henan Provincial Hospital. Zhengzhou 450000, Henan Province;
8. Department of Prosthodontics, Hospital of Stomatology, Wuhan University. Wuhan 430070, Hubei Province;
9. Department of Oral and Maxillofacial Surgery, Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University. Guangzhou 510055, Guangdong Province;
10. Department of Oral and Maxillofacial Surgery, The First Affiliated Hospital of Zhengzhou University. Zhengzhou 450052, Henan Province;
11. Department of Oral and Maxillofacial Surgery, Sun Yai-sen Memorial Hospital, Sun Yat-sen University. Guangzhou 510120, Guangdong Province;
12. Department of Oral and Maxillofacial Surgery, Xiangya Hospital, Central South University. Changsha 410008, Hunan Province;
13. Department of Radiology, School and Hospital of Stomatology, Wuhan University. Wuhan 430070, Hubei Province;
14. Department of Oral and Maxillofacial Surgery, Stomatological Hospital of Xiamen Medical College. Xiamen 361006, Fujian Province;
15. Department of Oral and Maxillofacial Surgery, The First Affiliated Hospital of University of Science and Technology of China. Hefei 230001, Anhui Province;
16. Department of Oral and Maxillofacial Surgery, West China Hospital of Stomatology, Sichuan University. Chengdu 610041, Sichuan Province;
17. Department of Oral Pathology, Peking University School of Stomatology. Beijing 100081, China

Received:2022-03-14 Revised:2022-03-26 Online:2022-05-20 Published:2022-05-20

摘要/Abstract

摘要： 牙源性角化囊肿（odontogenic keratocyst, OKC）是常见的良性颌骨囊性病损, 其局部侵袭性生长行为及显著的术后复发倾向,不同于常见的其他类型的颌骨囊肿,而该疾病的命名、分类、疾病性质以及治疗方法选择仍存在争议。随着 OKC 的相关研究深入、治疗理念和外科技术的发展,使降低术后复发率、同时合理保存和重建患者口腔结构和功能这一治疗目标成为可能。为提高OKC的临床诊疗水平,需要对其诊断、治疗、随访等方面进行必要的统一和规范。本专家共识汇集国内相关领域的多学科专家建议和临床实践经验,借鉴国内外相关研究成果,对 OKC 的病理机制、临床表现、影像学特征、组织病理学特点、治疗方法、治疗策略和随访等进行总结概括,以供临床医师参考。

关键词: 牙源性角化囊肿, 诊断, 治疗, 策略, 专家共识

Abstract: Odontogenic keratocyst (OKC) is a common cystic lesion of the jaw. The nomenclature and nature of OKC remain controversial as a result of its local invasive behavior and high tendency of recurrence, which is evidently different from other types of jaw cysts. With the in-depth study of OKC pathogenesis and the advance of treatment concept and surgical techniques, it becomes possible to reduce the rate of postoperative recurrence and simultaneous functional reconstruction of the jaw. To establish standard diagnosis and treatment algorithms or guidelines of OKC, we organized peer experts in China to reach a consensus on pathogenesis, clinical manifestations, imaging characteristics, histopathological features, surgery and postoperative follow-up strategies of OKC for the references of clinicians.

Key words: Odontogenic keratocyst, Diagnosis, Surgery, Strategy, Expert consensus

中图分类号:

R782.2

刘冰, 何悦, 彭歆, 孙长伏, 韩正学, 吴煜农, 彭利伟, 赵熠, 陶谦, 韩新光, 李劲松, 苏彤, 李波, 张雷, 胡砚平, 陈传俊, 李一, 李铁军, 赵怡芳. 牙源性角化囊肿诊疗中国专家共识[J]. 中国口腔颌面外科杂志, 2022, 20(3): 209-218.

LIU Bing, HE Yue, PENG Xin, SUN Chang-fu, HAN Zheng-xue, WU Yu-nong, PENG Li-wei, ZHAO Yi, TAO Qian, HAN Xin-guang, LI Jin-song, SU Tong, LI Bo, ZHANG Lei, HU Yan-ping, CHEN Chuan-jun, LI Yi, LI Tie-jun, ZHAO Yi-fang. Chinese Expert consensus on the diagnosis, treatment of odontogenic keratocyst[J]. China J Oral Maxillofac Surg, 2022, 20(3): 209-218.

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牙源性角化囊肿诊疗中国专家共识

Chinese Expert consensus on the diagnosis, treatment of odontogenic keratocyst

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