China Journal of Oral and Maxillofacial Surgery ›› 2024, Vol. 22 ›› Issue (4): 313-321.doi: 10.19438/j.cjoms.2024.04.001

• Expert Consensus • Previous Articles     Next Articles

Chinese expert consensus on diagnosis and treatment of localized intravascular coagulopathy

TAI Mao-zhong1, QIN Zhong-ping1, ZHENG Jia-wei2, LI Ke-lei1, LIU Xue-jian3, LI Kai4, YUAN Si-ming5, FAN Xin-dong6, ZHOU De-kai7, DONG Chang-xian8, JI Yi9, GU Song10, HUO Ran11, YANG Yao-wu12, WANG Xu-kai13   

  1. 1. Special Department of Vascular Anomalies, Tumor Hospital of Linyi City. Linyi 276001, Shandong Province;
    2. Department of Oromaxillofacial Head and Neck Oncology, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine. Shanghai 200011;
    3. Department of Oncology, First Rehabilitation Hospital of Shandong. Linyi 276000, Shandong Province;
    4. Department of Pediatric Surgery, Children's Hospital of Fudan University. Shanghai 201102;
    5. Department of Burn and Plastic Surgery, General Hospital of Eastern Theater Command,PLA-Jinling Hospital, Medical School of Nanjing University. Nanjing 210002, Jiangsu Province;
    6. Department of Intervention Therapy, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine. Shanghai 200011;
    7. Department of Infantile Hemangioma, Gastrointestinal and Neonatal Surgery, Children's Hospital of Chongqing Medical University. Chongqing 400014;
    8. Department of Hemangioma, Henan Provincial People’s Hospital. Zhengzhou 450003, Henan Province;
    9. Department of Pediatric Surgery, West China Hospital, Sichuan University. Chendu 610041, Sichuan Province;
    10. Department of Pediatric Oncologic Surgery, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine. Shanghai 200127;
    11. Department of Plastic and Esthetic Surgery, Medical Science and Technology Innovation Center, Shandong Provincial Hospital Affiliated to Shandong First Medical University. Jinan 250021, Shandong Province;
    12. Department of Maxillofacial Head and Neck Oncology, Air Force Medical University of PLA. Xi'an 710032, Shaanxi Province;
    13. Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, China Medical University. Shenyang 110002, Liaoning Province, China
  • Received:2023-03-20 Revised:2023-04-10 Online:2024-07-20 Published:2024-08-07

Abstract: Localized intravascular coagulopathy(LIC) refers to coagulation disorders such as thrombosis and bleeding that occurred in venous malformations(VMs). It is characterized by abnormally elevated D-dimer(DD) levels, with or without decreased fibrinogen(FIB), and generally without thrombocytopenia. LIC can be complicated with acute pain, excessive bleeding, arthrogryposis, etc. Controversies in its diagnosis and treatment still existed. In order to improve the diagnosis and standardize treatment of LIC in China, we invited relevant experts to discuss and formulate Chinese expert consensus. The consensus provides standardized suggestions on the pathogenesis, clinical manifestations, diagnostic methods and treatment process of LIC, which can provide reference for clinical practice.

Key words: Venous malformations, Localized intravascular coagulopathy, D-dimer, Fibrinogen, Expert consensus

CLC Number: