Expert consensus on clinical diagnosis and treatment for Chinese oral mucosal melanoma

doi:10.19438/j.cjoms.2021.06.001

China Journal of Oral and Maxillofacial Surgery ›› 2021, Vol. 19 ›› Issue (6): 481-488.doi: 10.19438/j.cjoms.2021.06.001

• Expert Consensus • Previous Articles Next Articles

Expert consensus on clinical diagnosis and treatment for Chinese oral mucosal melanoma

GUO Wei¹, REN Guo-xin¹, SUN Mo-yi², KONG Yun-yi³, WANG Li-zhen⁴, BU Rong-fa⁵, RAN Wei⁶, TANG Zhan-gui⁷, LI Long-jiang⁸, MENG Jian⁹, SUN Zhi-jun¹⁰, SHANG Wei¹¹, LV Jiong¹², WU He-ming¹³, ZHANG Chen-ping¹, HE Yue¹, MA Xu-hui¹, SONG Hao¹, JU Hou-yu¹, ZHENG Jia-wei¹, GONG Zhong-cheng¹⁴, YANG Kai¹⁵, ZHANG Jie¹⁶, WU Yun-teng¹

1. Department of Oromaxillofacial Head and Neck Oncology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine. Shanghai 200011;
2. Department of Oral and Maxillofacial Surgery, School of Stomatology, Air Force Medical University. Xi'an 710032, Shannxi Province;
3. Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai Medical College, Fudan University. Shanghai 200032;
4. Department of Oral Pathology, Shanghai Jiao Tong University School of Medicine. Shanghai 200011;
5. Department of Oral & Maxillofacial Surgery, People's Liberation Army Hospital. Beijing 100853;
6. Department of Stomatology, First Affiliated Hospital of Sun Yat-sen University. Guangzhou 510080, Guangdong Province;
7. Department of Oral and Maxillofacial Surgery, School of Medicine, Central South University. Changsha 410013, Hunan Province;
8. Department of Head and Neck Oncology, West China Stomatological Hospital, Sichuan University. Chengdu 610000, Sichuan Province;
9. Department of Stomatology, Xuzhou Central Hospital, School of Stomatology, Xuzhou Medical University. Xuzhou 221009, Jiangsu Province;
10. Department of Oromaxillofacial Head and Neck Oncology, Hospital of Stomatology Wuhan University. Wuhan 430079, Hubei Province;
11. Department of Oral and Maxillofacial Surgery, Affiliated Hospital of Qingdao University. Qingdao 266000, Shandong Province;
12. Department of Oral and Maxillofacial Surgery, First Affiliated Hospital of Zhejiang University Medical College. Hangzhou 310003, Zhejiang Province;
13. Department of Oral and Maxillofacial Surgery, Nanjing Medical University Stomatology College. Nanjing 210008, Jiangsu Province;
14. Department of Oral and Maxillofacial Surgery, First Affiliated Hospital of Xinjiang Medical University. Urumqi 830054, Xinjiang Uygur Autonomous Region;
15. Department of Oral and Maxillofacial Surgery, the First Affiliated Hospital of Chongqing Medical University. Chongqing 400042;
16. Department of Oral and Maxillofacial Surgery, Stomatological Hospital of Peking University. Beijing 100081, China

Online:2021-12-25 Published:2022-03-02

Abstract

Abstract: [Summary] Head and neck mucosal melanoma (HNMM) is a kind of highly malignant solid tumor. The 5-year survival rate of HNMM is about 20% for a long time. Its pathogenic factors, driving genes, clinical manifestations and treatment methods are quite different from skin melanoma. In 2015, the first Chinese expert consensus on the diagnosis and treatment of head and neck mucosal malignant melanoma was established. After more than six years of application, the clinical diagnosis and treatment of HNMM has been greatly improved. With the deepening of clinical and basic research on mucosal melanoma, the diagnosis, treatment and prognosis of HNMM have changed greatly in recent years, especially with the vigorous development of various branches of head and neck. Oral, nasal, sinus, eye and other mucosal melanoma have developed their own unique diagnosis and treatment model. This consensus can’t meet the actual needs of the current clinical practice. In this regard, the expert group believes that head and neck mucosa contains a wide range of anatomy, involving more clinical departments, and the diagnosis and treatment mode of melanoma varies significantly between different disciplines. It is urgent to meet the clinical consensus of more specialized diagnosis and treatment of individualized treatment and precise treatment. In order to further improve the long-term survival rate and quality of life of oral mucosal melanoma (OMM) and make the consensus to better guide clinical work, this expert group will focus on OMM and conduct in-depth discussion, and establish expert consensus based on evidence-based medicine and empirical medicine. Considering the individual differences of patients, this consensus can be used as a reference for clinical practice of OMM.

Key words: Oral cavity, Mucosal melanoma, Expert consensus

CLC Number:

R739.8

GUO Wei, REN Guo-xin, SUN Mo-yi, KONG Yun-yi, WANG Li-zhen, BU Rong-fa, RAN Wei, TANG Zhan-gui, LI Long-jiang, MENG Jian, SUN Zhi-jun, SHANG Wei, LV Jiong, WU He-ming, ZHANG Chen-ping, HE Yue, MA Xu-hui, SONG Hao, JU Hou-yu, ZHENG Jia-wei, GONG Zhong-cheng, YANG Kai, ZHANG Jie, WU Yun-teng. Expert consensus on clinical diagnosis and treatment for Chinese oral mucosal melanoma[J]. China Journal of Oral and Maxillofacial Surgery, 2021, 19(6): 481-488.

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Expert consensus on clinical diagnosis and treatment for Chinese oral mucosal melanoma

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