Abstract: Infantile hemangiomas IH are the most common vascular tumors of infancy. However, there are still some controversies over indications, pretreatment investigations, its use in PHACES syndrome as well as cessation of treatment. The present study applied a modified Delphi technique involving an international treatment survey, a systematic evidence review of the literature, a face-to-face multidisciplinary panel meeting and anonymous voting. The expert panel achieved consensus on 47 statements in eight categories eventually. This clinical guideline will contribute to standardize and simplify the treatment of IH with oral propranolol and assist in clinical decision-making.

Key words: Infantile hemangiomas, Propranolol, Clinical guidelines