Effect of rhizoma drynariae flavones on alveolar bone quality in patients with osteoporosis

doi:10.19438/j.cjoms.2018.01.007

Abstract

Abstract: PURPOSE: To evaluate the influence of rhizoma drynariae flavones on the height, thickness, bone mineral density of alveolar bone and width of the alveolar crest for osteoporosis patients with dentition defect or edentulous jaw. METHODS: Forty-six patients who met the inclusion criteria were randomly divided into 2 groups, the experimental group and the control group, 23 cases in each group. Cone-beam CT was performed for each patient before administration and 1 month, 3 months and 6 months after administration, respectively. Anatomage invivo 5 software was used to measure and observe the changes of alveolar bone height, thickness, bone mineral density and alveolar crest width. SPSS 17.0 software package was used for statistical analysis. RESULTS: In the control group, bone mineral density of cortical bone in the buccal (labial) side of the alveolar bone was significantly higher than that of the experimental group 1 months after administration (P<0.05). In the experimental group, bone mineral density of the buccal (labial) cortical bone was significantly higher than that of the control group 3 and 6 months after administration (P<0.05). Compared with the experimental group, the width of the alveolar crest and the thickness of cortical bone in the buccal (labial) side of the alveolar bone increased significantly 3 months after administration in the control group(P<0.05), yet there was no significant difference between the 2 groups at the end of 6 months (P>0.05). No significant difference was found on the thickness of cortical bone in the buccal (labial) side, cortical bone in the palatal(lingual) side and cancellous bone of the basal bone between the 2 groups at different time points (P>0.05). CONCLUSIONS: Rhizoma drynariae flavones can significantly increase bone mineral density of the alveolar bone in osteoporosis patients, which is superior to that of alendronate in increasing bone mineral density of cortical bone in the buccal (labial) side of the alveolar bone. Furthermore, rhizoma drynariae flavones can increase the thickness of cortical bone in the buccal (labial) side of the alveolar bone in patients with osteoporosis, but it has little effect on the width of alveolar crest and the height of alveolar bone.

Key words: Rhizoma drynariae flavones, Osteoporosis, Alveolar bone, Bone mineral density

CLC Number:

R782.1

YANG Feng, SUN Yu-hua, LV Zhong-jing, LIU Dian-bin, QIN Ying, XIAO Li-ting, SUN Jin-hu. Effect of rhizoma drynariae flavones on alveolar bone quality in patients with osteoporosis[J]. China Journal of Oral and Maxillofacial Surgery, 2018, 16(1): 34-40.

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