Clinical pathological and survival analysis of 160 head and neck osteosarcoma patients

Abstract

Abstract: PURPOSE: To analyze the clinical and histological factors of patients with head and neck osteosarcoma (HNOS) as well as the outcomes of followed-up patients. METHODS: The data were collected from HNOS patients treated in Shanghai Ninth People's Hospital. The variables included the patients' individual details, disease characteristics, treatment and follow up outcomes from 2007 to 2013. SPSS 17.0 software package was used for data analysis. RESULTS: One hundred and sixty patients' clinical and pathological information were obtained, 137 were followed up. The 5-year overall survival rate was 64.96%. Primary tumor, negative surgical margin, mandible tumor, neoadjuvant chemotherapy and adjuvant chemotherapy were factors associated with good prognosis. CONCLUSIONS: Negative surgical margin is important for good prognosis of patients with HNOS. Adjuvant and neoadjuvant chemotherapy can improve the survival.

Key words: Head and neck osteosarcoma, Clinical analysis, Pathological analysis, Survival analysis

CLC Number:

R739.8

WANG Yue-ping, CHEN Yi-ming, JI Tong. Clinical pathological and survival analysis of 160 head and neck osteosarcoma patients[J]. China Journal of Oral and Maxillofacial Surgery, 2017, 15(4): 349-353.

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