Guided bone regeneration and simultaneous implant placement using membrane in combination with titanium mesh for repair of alveolar defects in Beagle dogs

doi:10.19438/j.cjoms.2017.02.003

Abstract

Abstract: PURPOSE : To evaluate the effect of using guided bone regeneration (GBR) with (titanium) Ti mesh and Bio-Gide membrane in repair of alveolar bone defects in Beagle dogs. METHODS : Three mandibular premolars and one molar on both sides of the jaw in 3 dogs were extracted. Six months after extraction, three implants were inserted into each side, and alveolar bone defects (4 mm×4 mm×4 mm in size) were produced. 24 implants in total 6 sides were assigned to 3 groups and covered with different membranes as follows, group A: implant+Bio-Oss+Ti-mesh; group B: implant+Bio-Oss+Bio-Gide, group C: implant+Bio-Oss+Ti-mesh+Bio-Gide. The claps were sutured over the membranes to complete the wound closure. The animals were sacrificed after 6 months, and non-decalcified histological specimens of the implants and surrounding tissues were prepared. Micro-CT scanning was carried out to test the results. SPSS17.0 software package was used for statistical analysis. RESULTS : Micro-CT with three-dimensional reconstruction revealed that bone regeneration in group C was significantly better than the other two groups (P<0.01), which indicated faster new bone deposition. CONCLUSION S: Combination of Bio-Gide membrane and Ti-mesh may get a better bone regeneration than Ti-mesh or Bio-Gide used alone.

Key words: Guided bone regeneration, Titanium mesh, Alveolar defects, Tooth implant, Beagle dogs

CLC Number:

R782.1

LI Hui-ping, SUN Shou-fu, ZHEN Jin-ze, WANG Ye-xin, XU Wei-feng, ZHENG Ji-si, ZHANG Shan-yong, ZHU Ying-chao, ZHONG Xiao-qi. Guided bone regeneration and simultaneous implant placement using membrane in combination with titanium mesh for repair of alveolar defects in Beagle dogs[J]. China Journal of Oral and Maxillofacial Surgery, 2017, 15(2): 109-114.

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