Osseointegration study of SLM porous multi-rooted implants in rabbits

Abstract

Abstract: PURPOSE: The aim of this study was to develop a multi-rooted dental implant (MRI) with a connected porous surface structure to facilitate osseointegration. METHODS: MRIs manufactured by selective laser melting (SLM) and commercial implants with resorbable blasting media (RBM)-treated surfaces were inserted into the hind limbs of New Zealand white rabbits. Osseointegration was evaluated periodically over 12 weeks by micro-computerized tomography (CT) scanning, histological analysis, mechanical push-out tests, and torsion tests. The results were analyzed by using SPSS19.0 software package for ANOVA intra-group and un-paired t test. RESULTS: Bone volume densities were consistently higher in MRI group than in RBM group throughout the study period, ultimately resulting in a peak value of 48.41% for MRI. Histological analysis revealed denser surrounding bone growth in MRIs; after 4 and 8 weeks, bone tissue had grown into the pore structures and root bifurcation areas, respectively. Biomechanics tests indicated binding of the porous MRIs to the neobone tissues, as push-out forces strengthened from 294.7 N to 446.5 N and maximum mean torsion forces improved from 81.2 N to 289.6 N(MRI), versus 34.8 N to 87.8 N in the RBM group. CONCLUSIONS: MRIs manufactured by SLM possess a connected porous surface structure that improves the osteogenic characteristics of the implant surface and may promote implant survival.

Key words: Implant design, Biomechanics, Selective laser melting, Multi-rooted implant, Osseointegration

CLC Number:

R782.1

ZHANG Qing, OU Yue-jian, YOU Jia, XU Hai-yan, SUN Qi-jun. Osseointegration study of SLM porous multi-rooted implants in rabbits[J]. China Journal of Oral and Maxillofacial Surgery, 2016, 14(5): 397-403.

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