Histological change of rabbit oral mucosa after fractional Er:YAG laser irradiation

China Journal of Oral and Maxillofacial Surgery ›› 2015, Vol. 13 ›› Issue (2): 117-123.

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Histological change of rabbit oral mucosa after fractional Er:YAG laser irradiation

TIAN Hai-suo^{1, 2}, LIN Dong-peng¹, ZHAO Tian-yi¹, YU Bo¹, MA Qin¹

1.State Key Laboratory of Military Stomatology, Department of Oral and Maxillofacial Surgery, School of Stomatology, The Forth Military Medical University. Xi'an 710032, Shaanxi Province;
2. Department of Stomatology, Armed Police Corps Hospital in Liaoning Province. Shenyang 110034, Liaoning Province, China

Received:2014-09-25 Revised:2014-11-27 Online:2015-03-20 Published:2015-04-23
Supported by:
Supported by Science and Technology Research Planning Project of Shaanxi Province (2012SF2-20-2)

Abstract

Abstract: PURPOSE: Histological changes were studied to evaluate the effect of fractional Er:YAG laser treatment on oral mucosa tissues. METHODS: The rabbit oral mucosa was irradiated with Er:YAG laser. The epithelial thickness, lamina propria collagen fiber and elastic fiber content were assessed at 1, 2, 4 weeks after OP. H-E staining, Masson staining and elastic fiber staining were utilized. The experimental results were statistically analyzed by SPSS19.0 software package. RESULTS: After dot matrix Er:YAG irradiation, mucosal damage zone was limited only within the mucosal epithelium, and healed completely in 3-7 days, without leaving scar and pigment. The epithelial thickness was increased significantly (P<0.05), and the lamina propria collagen fiber and elastic fiber content were increased significantly (P< 0.05). After fractional Er:YAG laser irradiation, the rabbit had a small oral mucosa lesion and healed quickly. The epithelial remodeled. The mucosa lamina propria collagen contracted. CONCLUSIONS: After fractional Er:YAG laser irradiation, collagen fiber and elastic fiber proliferated and remodeled. The mucosa was tightening and the mucous membrane elasticity was increased.

Key words: Er:YAG Laser, Collagen fiber, Elastic fiber, Rabbit

CLC Number:

R782.2

TIAN Hai-suo, LIN Dong-peng, ZHAO Tian-yi, YU Bo, MA Qin. Histological change of rabbit oral mucosa after fractional Er:YAG laser irradiation[J]. China Journal of Oral and Maxillofacial Surgery, 2015, 13(2): 117-123.

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Histological change of rabbit oral mucosa after fractional Er:YAG laser irradiation

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