Chondrosarcoma in the temporomandibular joint with skull base invasion: a case report

doi:10.19438/j.cjoms.2026.05.013

Abstract

Abstract: Temporomandibular joint chondrosarcoma is clinically rare, and its diagnosis and surgical management become significantly more challenging when the tumor invades the skull base. This article reported a case of highly differentiated temporomandibular joint chondrosarcoma involving and destroying the middle cranial fossa. The complete resection of the skull base tumor in the temporal fossa was performed under computer-assisted surgical navigation, combined with mandibular condylectomy. Key diagnostic and therapeutic principles are summarized based on imaging findings, intraoperative observations, and pathological immunohistochemical results, with a review of relevant domestic and international literature, providing reference for the clinical management of this rare lesion.

Key words: Temporomandibular joint, Chondrosarcoma, Skull base, Mandibular condylectomy

CLC Number:

R739.8

Gong Yuze, Xue Jiao, Wang Qimin, Jiang Yuanzheng, Qiu Jianzhong, Yuan Rongtao. Chondrosarcoma in the temporomandibular joint with skull base invasion: a case report[J]. China Journal of Oral and Maxillofacial Surgery, 2026, 24(5): 527-531.

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