Oral verrucous xanthoma: a case report and literature review

doi:10.19438/j.cjoms.2026.02.016

China Journal of Oral and Maxillofacial Surgery ›› 2026, Vol. 24 ›› Issue (2): 196-199.doi: 10.19438/j.cjoms.2026.02.016

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Oral verrucous xanthoma: a case report and literature review

Shao Yu^1,2, Yu Wenyuan¹, Xu Yong³, Xu Jin³, Chen Zhenggang^3,4

1. School of Stomatology, Shandong Second Medical University. Weifang 261053;
2. Department of Stomatology, Qingdao Hospital, University of Health and Rehabilitation Sciences (Qingdao Municipal Hospital). Qingdao 266011;
3. School of Stomatology, Binzhou Medical University. Yantai 264003;
4. The Affiliated Yantai Stomatological Hospital, Binzhou Medical University. Yantai 264000, Shandong Province, China

Received:2025-07-18 Revised:2025-08-21 Online:2026-03-20 Published:2026-04-02

Abstract

Abstract: Verruciform xanthoma (VX) is a rare benign lesion of the skin and mucous membranes with an atypical clinical presentation that makes it easy to misdiagnose. The diagnosis can usually only be confirmed by histopathology, and its diagnostic hallmark is the finding of large foam cell aggregates in connective tissue papillae between extended epithelial pegs. This paper reported a case of verrucous xanthoma of the left palate, which was misdiagnosed as highly differentiated gingival carcinoma during consultation at a local hospital, and was diagnosed as verrucous xanthoma after resection and histopathologic examination at our hospital. Combined with a review of relevant literature, this article discussed the causes of misdiagnosis, aiming to reduce or avoid such misdiagnoses in clinical practice.

Key words: Verrucous xanthoma, Oral tumor, Oral mucosal lesions

CLC Number:

R739.8

Shao Yu, Yu Wenyuan, Xu Yong, Xu Jin, Chen Zhenggang. Oral verrucous xanthoma: a case report and literature review[J]. China Journal of Oral and Maxillofacial Surgery, 2026, 24(2): 196-199.

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Oral verrucous xanthoma: a case report and literature review

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