Therapeutic effect of individualized template-guided 125I seed implants for unresectable malignant salivary gland tumors

doi:10.19438/j.cjoms.2017.02.009

Abstract

Abstract: PURPOSE : To evaluate the short-term effect of individualized template guided 125I seed implants for advanced unresectable malignant salivary gland tumors, and explore its superiority. METHODS : Fourteen patients with histologically documented advanced unresectable malignant salivary gland tumors were treated by radioactive 125I seeds interstitial implantation under the aid of individualized template guide. The treatment response, distribution of seeds, local control rate and survival rate were evaluated and the adverse events observed. RUSULTS: The actuarial median number of 125I seeds treated was 43, and actuarial median D90,V100,V150 was 186.2 Gy, 98.2%, 43.4%, respectively; The average radiation dose received by the eyes and brain was 3.2 Gy, 32.5 Gy, respectively; The overall response rate was 78.3%. The patients were followed up for 15 to 28 months (median 23 months). The local control rate was 78.6%, and overall survival rate was 78.6%. No serious side radiotherapeutic effect was observed. CONCLUSION S: The method of individualized template-guided 125I seed implants for advanced unresectable malignant salivary gland tumors is feasible, minimally invasive, safe and easy to operate, which can be widely used in clinical practice.

Key words: Head and neck neoplasms, Adenogenous malignant tumor, ¹²⁵I seeds, Individualized template, Brachytherapy

CLC Number:

R782.4

ZHENG Hao, YANG Xu-dong, Meng Jian. Therapeutic effect of individualized template-guided ¹²⁵I seed implants for unresectable malignant salivary gland tumors[J]. China Journal of Oral and Maxillofacial Surgery, 2017, 15(2): 142-146.

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Therapeutic effect of individualized template-guided ¹²⁵I seed implants for unresectable malignant salivary gland tumors

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