Chinese expert consensus on diagnosis and treatment of Kasabach-Merritt phenomenon

doi:10.19438/j.cjoms.2019.02.001

China Journal of Oral and Maxillofacial Surgery ›› 2019, Vol. 17 ›› Issue (2): 97-105.doi: 10.19438/j.cjoms.2019.02.001

• Expert Consensus • Previous Articles Next Articles

Chinese expert consensus on diagnosis and treatment of Kasabach-Merritt phenomenon

LI Ke-lei¹, YAO Wei², QIN Zhong-ping¹, LI Kai², ZHENG Jia-wei³, FAN Xin-dong⁴, MA Lin⁵, ZHOU De-kai⁶, LIU Xue-jian⁷, WEI Li⁵, LI Li⁵, TAI Mao-zhong¹, WANG Jin-hu⁸, JI Yi⁹, ZHOU Ling¹⁰, HUANG Hai-jin¹¹, GAO Xiao-yun¹², HUANG Zhi-jian¹³, GU Song¹⁴, YANG He-ying¹⁵

1. Special Department of Hemangioma, Tumor Hospital of Linyi City. Linyi 276001, Shandong Province;
2. Department of Pediatric Surgery, Children's Hospital of Fudan University. Shanghai 201102;
3.Department of Oral and Maxillofacial Surgery, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine. Shanghai 200011;
4. Department of Intervention Therapy, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine. Shanghai 200011;
5.Department of Dermatology, Beijing Children's Hospital affiliated to Capital Medical University. Beijing 100045;
6. Department of Infantile Hemangioma, Gastrointestinal and Neonatal Surgery, Children's Hospital of Chongqing Medical University. Chongqing 400014;
7. Department of Oncology, People's Hospital of Linyi Economic Development Zone. Linyi 276023, Shandong Province;
8. Department of Pediatric Surgery, Children's Hospital, Zhejiang University School of Medicine. Hangzhou 310003, Zhejiang Province;
9. Department of Pediatric Surgery, West China Hospital, Sichuan University. Chendu 610041, Sichuan Province;
10. Department of Pediatric Surgery, People's Hospital of Xinjiang Uygur Autonomous Region. Urumchi 830001, Xinjiang Uygur Autonomous Region;
11. Department of Pediatric Surgery, First Affiliated Hospital of Gannan Medical University. Ganzhou 341000, Jiangxi Province;
12. Department of Pediatric Surgery, Fujian Provincial Hospital. Fuzhou 350001, Fujian Province;
13. Department of Pediatric Surgery, Children's Hospital of Soochow University. Suzhou 215025, Jiangsu Province;
14. Department of Pediatric Surgery, Shanghai Children's Medical Center. Shanghai 200127;
15. Department of Pediatric Surgery, The first Affiliated Hospital of Zhengzhou University. Zhengzhou 450052, Henan Province, China

Received:2019-01-08 Revised:2019-02-10 Online:2019-03-20 Published:2019-04-12

Abstract

Abstract: Kasabach-Merritt phenomenon (KMP) is characterized by severe thrombocytopenia and consumptive coagulation dysfunction caused by Kaposiform hemangioendothelioma or tufted angioma. KMP is predominant in infants and little children and is often with rapid progress. If KMP is not diagnosed and treated in time, it can cause serious complications and even endanger life. In view of the current controversies in the diagnosis and treatment of KMP, and in order to improve the diagnosis level and standardize treatment of KMP in China, we invited relevant experts to discuss and formulate Chinese expert consensus. The consensus provides standardized suggestions on the pathogenesis, clinical manifestations, diagnostic methods and treatment process of KMP, which can provide reference for clinical practice.

Key words: Kasabach-Merritt phenomenon, Kaposiform hemangioendothelioma, Tufted angioma, Expert consensus

CLC Number:

R739.8

LI Ke-lei, YAO Wei, QIN Zhong-ping, LI Kai, ZHENG Jia-wei, FAN Xin-dong, MA Lin, ZHOU De-kai, LIU Xue-jian, WEI Li, LI Li, TAI Mao-zhong, WANG Jin-hu, JI Yi, ZHOU Ling, HUANG Hai-jin, GAO Xiao-yun, HUANG Zhi-jian, GU Song, YANG He-ying. Chinese expert consensus on diagnosis and treatment of Kasabach-Merritt phenomenon[J]. China Journal of Oral and Maxillofacial Surgery, 2019, 17(2): 97-105.

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Chinese expert consensus on diagnosis and treatment of Kasabach-Merritt phenomenon

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