Research advances in PHACES syndrome

Abstract

Abstract: Hemangiomas are the most common benign tumors in infancy, and in rare cases, they can be associated with dysmorphic malformation. The acronym, PHACES syndrome is a cutaneous condition characterized by multiple congenital abnormalities, including: posterior fossa brain malformations, hemangiomas of the face, arterial cerebrovascular anomalies, cardiovascular anomalies, eye anomalies and sternal defects/supraumbilical raphe. Its prevalence is unknown, but has a striking female preponderance. Among the systemic abnormalities, neurological and cardiac malformations predominate. PHACES syndrome had been recognized as a new and independent entity. This review highlighted the recent findings in clinical feature, diagnosis and management of PHACES syndrome.

Key words: PHACES syndrome, Hemangioma, Vascular malformation

CLC Number:

R739.8

ZHANG Ling, ZHENG Jia-wei. Research advances in PHACES syndrome[J]. China Journal of Oral and Maxillofacial Surgery, 2016, 14(5): 467-470.

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