A perspective of evidence-based medicine on exploring the treatment strategy of head and neck cancer in pregnancy

doi:10.19438/j.cjoms.2024.02.002

Abstract

Abstract: The occurrence of malignant tumor during pregnancy is relatively rare, but with the increased age of pregnant women and the decreased age of patients suffering from head and neck cancer(HNC), the incidence of HNC complicated with pregnancy is slightly increasing. However, at present, there has been a lack of standardized diagnosis and treatment standards for pregnant woman with HNC. This paper evaluated the frequency, tumor type, associated factors, and specific biomarkers in HNCs occurring in pregnant women (including peripartum), based on systematic literature retrieval that performed on PubMed databank. From an evidence-based medicine view, this review presents a comprehensive description of the studies of pregnancy complicated with HNC, and intends to provide guidance in clinical practice.

Key words: Head and neck cancer, Pregnant woman, Retrospective analysis, Immunology, Molecular biology

CLC Number:

R739.8

LI Chen-xi, DING Yi, LIU Hui, GONG Zhong-cheng, ZHANG Wei-na, ZHAO Hua-rong. A perspective of evidence-based medicine on exploring the treatment strategy of head and neck cancer in pregnancy[J]. China Journal of Oral and Maxillofacial Surgery, 2024, 22(2): 118-127.

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