Osteomyelitis of the mandible associated with malignant infantile osteopetrosis:a case report and literature review

Abstract

Abstract: Osteopetrosis is a rare congenital genetic disease characterized by increased bone density due to impaired bone resorption by osteoclasts. The incidence of autosomal recessive osteopetrosis, also called malignant infantile osteopetrosis, is 1:300000. This article presented a typical case of osteomyelitis of the mandible associated with malignant infantile osteopetrosis, and reviewed the relevant literature on the pathogenesis, clinical manifestations, radiological feature and treatment of osteopetrosis.

Key words: Osteopetrosis, Malignant infantile osteopetrosis, Osteomyelitis of the mandible

CLC Number:

R782.3

WANG Jie-qi, ZHANG Da-ming, ZHENG Mei-hua, CHEN Wei-liang. Osteomyelitis of the mandible associated with malignant infantile osteopetrosis:a case report and literature review[J]. China Journal of Oral and Maxillofacial Surgery, 2014, 12(6): 573-576.

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