China Journal of Oral and Maxillofacial Surgery ›› 2025, Vol. 23 ›› Issue (5): 527-531.doi: 10.19438/j.cjoms.2025.05.016

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Advances in the study of retrograde peri-implantitis

Chen Yan1, Sun Jiahui2, Yan Qi1, Chen Jiaxian1, Wang Li3   

  1. 1. Department of Oral Implantology, School & Hospital of Stomatology, Wuhan University. Wuhan 430079;
    2. Department of Periodontics, School & Hospital of Stomatology, Wuhan University; State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration; Key Laboratory of Oral Bio-medicine Ministry of Education; Hubei Key Laboratory of Stomatology. Wuhan 430079;
    3. Department of Nursing, School & Hospital of Stomatology, Wuhan University. Wuhan 430079, Hubei Province, China
  • Received:2024-11-21 Revised:2025-02-04 Published:2025-10-10

Abstract: Complications of implant restorations include surgical, mechanical and biological complications, of which peri-implantitis is the most common biological complication. Retrograde peri-implantitis is an inflammatory lesion in the apical region of the implant, which often leads to early failure of implant restorations. Its etiology is multiple and complex, and preoperative evaluation and intraoperative operational factors are crucial to take effective measures to control the development of the lesion and to improve the survival rate of implant retention. This article summarised the current status of research on the definition, prevalence, etiology, clinical manifestations and classification, treatment options and prognosis of retrograde peri-implantitis, with a view to providing a reasonable basis for clinical decision-making in the treatment of retrograde peri-implantitis.

Key words: Implant restoration, Biological complications, Retrograde peri-implantitis, Implant apical lesions

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