Abstract: PURPOSE: To investigate the effect of platelet-rich plasma(PRP) combined with coral bone powder on implant restoration in edentulous patients with insufficient bone mass in the anterior esthetic zone. METHODS: A total of 106 patients who underwent implant restoration in the aesthetic area of anterior teeth in Beijing Changping Hospital of Traditional Chinese Medicine from January 2018 to January 2023 were selected. The control group(n=52 ) received coral bone powder + Bio-Gide collagen membrane coverage during surgery, while the experimental group(n=54) received coral bone powder + PRP + Bio-Gide collagen membrane coverage during surgery. After 6 months of postoperative follow-up, the success rate of implantation, height of the sinus floor, thickness of the labial side bone, density of the labial side bone, bleeding index (BI), probing depth (PD), attachment loss (AL), pink aesthetic score(PES), and white aesthetic score(WES) were compared between the two groups, and postoperative complications were recorded. SPSS 24.0 software package was used for data analysis. RESULTS: At 6 months after operation, there was no significant difference in the success rate of implantation between the experimental group (100.00%, 54/54) and the control group (98.08%,51/52) (P>0.05). The labial bone thickness of the experimental group and control group were (1.71±0.39) and (1.34±0.35) mm, and the labial bone density were (1.89±0.36) and (1.65±0.41) g/cm², respectively, which were significantly higher in the experimental group than in the control group(P<0.05). The proportion of sinus floor bone height increase >2 mm in the experimental group was significantly higher than that in the control group(P<0.05). At 6 months after crown restoration, BI, PD and CAL in the experimental group were significantly lower than those in the control group (P<0.05), PES and WES scores in the experimental group were significantly higher than those in the control group (P<0.05). There was no significant difference in the incidence of complications between the two groups(P>0.05). CONCLUSIONS: The application of PRP combined with coral bone powder in the implant restoration of patients with insufficient bone mass in the anterior esthetic area can help to improve the sinus floor and labial bone increment, and improve the aesthetic effect of dental implantation with good safety.

Key words: Dental implantation, Aesthetic area of anterior teeth, Insufficient bone mass, Platelet rich plasma, Coral bone powder, Bone increment