The effect of botox A combined with pulsed dye laser on preventing scar hyperplasia after maxillofacial surgery

doi:10.19438/j.cjoms.2025.01.011

Abstract

Abstract: PURPOSE: To investigate the effect of botulinum toxin A combined with pulsed dye laser on preventing scar hyperplasia in maxillofacial surgical incisions. METHODS: A total of 92 patients receiving maxillofacial surgery at the Department of Stomatology of 904 Hospital of the Joint Logistic Support Force of PLA from August 2019 to December 2022 were selected and divided into the experimental group(n=46) and the control group(n=46) by random number table method. Pulsed dye laser (PDL) combined with botox type A was used in the experimental group to prevent scar hyperplasia of surgical incision, while botox type A alone was used in the control group. The clinical efficacy, scar status, patient satisfaction and adverse reactions were compared between the two groups. SPSS 22.0 software package was used for data analysis. RESULTS: The total effective rate of the experimental group was 84.78%, which was significantly higher than that of the control group(63.04%, P<0.05). There were no significant differences in scar color, flatness, elasticity and scar width scores between the two groups before treatment(P>0.05). After 1 week of treatment, scar color, flatness, elasticity and scar width scores between the two groups were significantly lower than before treatment, and the experimental group was significantly lower than the control group (P<0.05). The total satisfaction of the experimental group was significantly higher than that of the control group(P<0.05). There was no significant difference between the experimental group and the control group in the situation of detensioning suture, the location of the wound at the prone site of scar hyperplasia and the presence of scar tension (P>0.05). There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05). CONCLUSIONS: The combination of type A botulinum toxin and pulsed dye laser has a good effect and high safety in preventing scar hyperplasia in maxillofacial surgical incisions, and can be widely used in clinical practice.

Key words: Type A botulinum toxin, Pulsed dye laser, Maxillofacial surgery, Scar hyperplasia, POSAS rating

CLC Number:

R782

MA Cheng, ZHANG Yan, MA Xu. The effect of botox A combined with pulsed dye laser on preventing scar hyperplasia after maxillofacial surgery[J]. China Journal of Oral and Maxillofacial Surgery, 2025, 23(1): 62-66.

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