Application of preoperative enteral nutrition support in patients with oral squamous cell carcinomas in the enhanced recovery after surgery

doi:10.19438/j.cjoms.2020.02.006

Abstract

Abstract: PURPOSE： To evaluate the effect of preoperative enteral nutrition support for patients with oral squamous cell carcinomas. METHODS: Fifty-six patients with oral squamous cell carcinoma were divided into experimental group (n=37) and control group (n=19). On the basis of routine diet, patients in the experimental group received oral nutritional preparations for more than 7 days before operation, while patients in the control group received routine diet before operation. The changes of body mass index, serum albumin, serum prealbumin, serum ion concentration, nutrition-related adverse reactions, complications, first exhaust time, hospital stay and total hospitalization expenses were recorded. SPSS 17.0 software package was used for data input and analysis. RESULTS: The serum albumin, at 7 days prealbumin and body mass index, at 3 days and 7 days after operation in the experimental group were significantly higher than those in the control group; the incidence of nausea, vomiting, diarrhea and constipation in the experimental group was significantly lower than that in the control group; the experimental group was significantly lower than that in the control group at the first time of exhaust after operation; the duration of hospitalization and the total cost of hospitalization in the experimental group were significantly shortened (P<0.05). CONCLUSIONS: Preoperative enteral nutrition support is a safe and effective treatment for oral squamous cell carcinoma patients. It can improve the nutritional status of patients after operation, effectively reduce the incidence of nutrition-related adverse reactions after operation, shorten the length of hospital stay after operation and reduce the cost of hospitalization.

Key words: Enteral nutrition, Oral cancer, Pre-adaptation, Enhanced recovery after surgery

CLC Number:

R739.8

WANG Yan, JIANG Tong-hui, ZHUANG Hai, ZHANG Ji-sheng, BU Shou-shan.. Application of preoperative enteral nutrition support in patients with oral squamous cell carcinomas in the enhanced recovery after surgery[J]. China Journal of Oral and Maxillofacial Surgery, 2020, 18(2): 122-126.

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