China Journal of Oral and Maxillofacial Surgery ›› 2019, Vol. 17 ›› Issue (6): 554-559.doi: 10.19438/j.cjoms.2019.06.015

• Clinical Guidelines • Previous Articles     Next Articles

Clinical practice guidelines for CLOVES syndrome (translation version)

ZHANG Ling1, CHEN Zheng-gang2, ZHENG Jia-wei1   

  1. 1.Department of Oromaxillofacial Head and Neck Oncology, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine; National Clinical Research Center for Oral Disease;Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology. Shanghai 200011;
    2.Department of Oral and Maxillofacial Surgery, Qingdao Municipal Hospital Group. Qingdao 266011, Shandong Province, China
  • Received:2019-05-28 Online:2019-11-20 Published:2019-12-16

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Abstract: CLOVES syndrome is a rare congenital vascular disorder with the following clinical features: congenital lipomatous overgrowth, vascular malformations, epidermal nevi, scoliosis/skeletal/spional anomalie. The etiology and pathogenesis remain unknown. Symptoms and severity of CLOVES vary greatly among each individual. The goals of treatment are to alleviate symptoms and minimize the risk of complications. This article reviewed the clinical presentation and diagnostic studies, and provided management guidelines to help care for patients with this syndrome.

Key words: CLOVES syndrome, Congenital lipomatous overgrowth, Vascular malformations, Epidermal nevi, Scoliosis, Skeletal anomalies, Spional anomalies, Clinical practice guidelines

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