口腔微生物与口腔鳞状细胞癌关系的研究进展

doi:10.19438/j.cjoms.2020.03.018

摘要/Abstract

摘要： 口腔微生物群落在人类微生物群落和人类健康中发挥着重要作用,微生物与宿主的不平衡可导致口腔疾病和全身疾病。一些肿瘤已经被认为与细菌等微生物的存在相关,口腔肿瘤和微生物的关系也被逐渐认识。本文对口腔鳞状细胞癌与口腔微生物之间的关系进行综述,阐述口腔微生物导致口腔鳞状细胞癌发生的可能途径以及口腔鳞状细胞癌微环境对微生物的影响,为口腔微生物与肿瘤关系的进一步研究提供参考,以实现口腔鳞状细胞癌早期诊断,甚至辅助治疗的目的。

关键词: 口腔, 鳞状细胞癌, 微生物, 牙龈卟啉单胞菌, 白色念珠菌

Abstract: Oral microflora plays an important role in human microflora and human health, the imbalance between microbes and their hosts leads to oral and systemic diseases. Some tumors have been considered to be related to the existence of bacteria and other microorganisms, and the relationship between oral tumors and microorganisms has been gradually recognized. This paper reviewed the relationship between oral squamous cell carcinoma and oral microorganisms, and expounded the possible pathway of oral squamous cell carcinoma caused by oral microorganisms and the influence of oral squamous cell carcinoma microenvironment on microorganisms, in order to provide reference for further research on the relationship between oral microbe and tumor, so as to realize the purpose of early diagnosis of oral squamous cell carcinoma and even adjuvant therapy.;

Key words: Oral cavity, Squamous cell carcinoma, Microorganisms, Porphyromonas gingivalis, Candida albicans

中图分类号:

R739.8

刘塬, 张凌. 口腔微生物与口腔鳞状细胞癌关系的研究进展[J]. 中国口腔颌面外科杂志, 2020, 18(3): 278-284.

LIU Yuan, ZHANG Ling. Advances in the relationship between oral microbe and oral squamous cell carcinoma[J]. China J Oral Maxillofac Surg, 2020, 18(3): 278-284.

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