颌面部麻木的检测及其治疗进展

doi:10.19438/j.cjoms.2019.06.018

中国口腔颌面外科杂志 ›› 2019, Vol. 17 ›› Issue (6): 571-574.doi: 10.19438/j.cjoms.2019.06.018

颌面部麻木的检测及其治疗进展

郝昀博, 张伟杰, 陈敏洁

上海交通大学医学院附属第九人民医院·口腔医学院口腔外科,国家口腔疾病临床医学研究中心, 上海市口腔医学重点实验室,上海市口腔医学研究所,上海 200011

收稿日期:2018-11-08 出版日期:2019-11-20 发布日期:2019-12-16
通讯作者: 张伟杰,E-mail:zwj1891502@sina.com;陈敏洁,E-mail:chenminjie00@126.com。#共同通信作者
作者简介:郝昀博(1994-),男,硕士,E-mail: 812743624@qq.com。
基金资助:
上海交通大学医学院附属第九人民医院临床研究型MDT项目（201701018）

Detection and treatment progress of facial numbness

HAO Yun-bo, ZHANG Wei-jie, CHEN Min-jie

Department of Oral Surgery, Shanghai Ninth People's Hospital,College of Stomatology, Shanghai Jiao Tong University School of Medicine; National Clinical Research Center for Oral Diseases, Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology. Shanghai 200011,China;

Received:2018-11-08 Online:2019-11-20 Published:2019-12-16

摘要/Abstract

摘要： 麻木是临床上常见的一种症状,大多伴随神经自身病变,或多种原因导致的神经损伤。目前对麻木的检测采用主观评价方法,电生理评价方法有待明确。而关于麻木的治疗,除了去除病因外,多采用神经营养药物以及神经松解等促进神经恢复的方法。本文对麻木的检测方法及近年来针对麻木的治疗进展进行综述。

关键词: 麻木, 感觉障碍, 神经损伤, 三叉神经

Abstract: Numbness is a kind of sensory loss, commonly seen in the limbs and face. Because facial feeling is sensitive, numbness that occurs in the face brings great degree of disturbance to the patient's life, work, social intercourse and so on. At present, subjective evaluation method is used for detection of numbness, and the method of electrophysiological evaluation needs to be clarified. As for the treatment of numbness, in addition to removing the causes,use of neurotrophic drugs, nerve relaxation and other methods to promote nerve recovery were used increasingly. This review presented the methods of numbness detection and the treatment of numbness in recent years.

Key words: Numbness, Sensory disturbance, Nerve injury, Trigeminal nerve

中图分类号:

R745.1

郝昀博, 张伟杰, 陈敏洁. 颌面部麻木的检测及其治疗进展[J]. 中国口腔颌面外科杂志, 2019, 17(6): 571-574.

HAO Yun-bo, ZHANG Wei-jie, CHEN Min-jie. Detection and treatment progress of facial numbness[J]. China J Oral Maxillofac Surg, 2019, 17(6): 571-574.

参考文献

[1] Kou W, Gareus I, Bell JD, et al.Quantification of DeQi sensation by visual analog scales in healthy humans after immunostimulating acupuncture treatment[J]. Am J Chin Med, 2007, 35(5): 753-765.
[2] Ziccardi VB, Dragoo J, Eliav E, et al.Comparison of current perception threshold electrical testing to clinical sensory testing for lingual nerve injuries[J]. J Oral Maxillofac Surg, 2012, 70(2): 289-294.
[3] Ido Y, Uchiyama S, Nakamura K, et al.Postoperative improvement in DASH score, clinical findings, and nerve conduction velocity in patients with cubital tunnel syndrome[J]. Sci Rep, 2016, 6: 27497.
[4] Takazakura D, Ueki K, Nakagawa K, et al.A comparison of postoperative hypoesthesia between two types of sagittal split ramus osteotomy and intraoral vertical ramus osteotomy, using the trigeminal somatosensory-evoked potential method[J]. Int J Oral Maxillofac Surg, 2007, 36(1): 11-14.
[5] Isak B, Tankisi H, Johnsen B, et al.Laser and somatosensory evoked potentials in amyotrophic lateral sclerosis[J]. Clin Neurophysiol, 2016, 127(10): 3322-3328.
[6] Younis S, Maarbjerg S, Reimer M, et al.Quantitative sensory testing in classical trigeminal neuralgia-a blinded study in patients with and without concomitant persistent pain[J]. Pain, 2016, 157(7): 1407-1414.
[7] Kim HK, Kim KS, Kim ME.Thermal perception as a key factor for assessing effects of trigeminal nerve injury[J]. J Oral Facial Pain Headache, 2017, 31(2): 129-138
[8] Chhabra A, Ahlawat S, Belzberg A, et al.Peripheral nerve injury grading simplified on MR neurography: As referenced to Seddon and Sunderland classifications[J]. Indian J Radiol Imaging, 2014, 24(3): 217-224
[9] Seddon HJ.Three types of nerve injury[J]. Brain, 1943, 66(4): 237-288.
[10] Sunderland S.A classification of peripheral nerve injuries producing loss of function[J]. Brain, 1951, 74(4): 491-516.
[11] 潘明锐. 前列地尔联合甲钴胺治疗糖尿病周围神经病变的临床效果[J]. 中国处方药, 2014, 12(11): 48-49.
[12] Schenck K, Schreurs O, Hayashi K, et al.The role of nerve growth factor (NGF) and its precursor forms in oral wound healing[J]. Int J Mol Sci, 2017, 18(2): E386.
[13] Bendella H, Rink S, Grosheva M, et al.Putative roles of soluble trophic factors in facial nerve regeneration, target reinnervation, and recovery of vibrissal whisking[J]. Exp Neurol, 2018, 300: 100-110.
[14] Zhao YZ, Jiang X, Xiao J, et al.Using NGF heparin-poloxamer thermosensitive hydrogels to enhance the nerve regeneration for spinal cord injury[J]. Acta Biomater, 2016, 29: 71-80.
[15] Liang YJ, He WJ, Zheng PB, et al.Inferior alveolar nerve function recovers after decompression of large mandibular cystic lesions[J]. Oral Dis, 2015, 21(5): 674-678.
[16] Yu Q, Chen C, Zhang X, et al.Quantitative assessment of the motor-sensory specificity of the motor and primary sensory neurons after the end-to-side neurorrhaphy[J]. J Reconstr Microsurg, 2013, 29(9): 579-586.
[17] Deng JX, Zhang DY, Li M, et al.Autologous transplantation with fewer fibers repairs large peripheral nerve defects[J]. Neural Regen Res, 2017, 12(12): 2077-2083.
[18] Barbour JR, Yee A, Moore AM, et al.Cadaveric nerve allotransplantation in the treatment of persistent thoracic neuralgia[J]. Ann Thorac Surg, 2015, 99(4): 1414-1417.
[19] Singh B, Xu QG, Franz CK, et al.Accelerated axon outgrowth, guidance, and target reinnervation across nerve transection gaps following a brief electrical stimulation paradigm[J]. J Neurosurg, 2012, 116(3): 498-512.
[20] Calvey C, Zhou W, Stakleff KS, et al.Short-term electrical stimulation to promote nerve repair and functional recovery in a rat model[J]. J Hand Surg Am, 2015, 40(2): 314-322.
[21] Phillips C, Kim SH, Tucker M, et al.Sensory retraining: burden in daily life related to altered sensation after orthognathic surgery, a randomized clinical trial[J]. Orthod Craniofac Res, 2010, 13(3): 169-178.
[22] 张丹, 张春红. 中风后肢体麻木治疗研究进展[J]. 山东中医杂志, 2015, 34(12): 972-973.
[23] 李登振, 董赟. 针灸治疗中风后麻木的研究进展[J]. 中医药临床杂志, 2017, 29(3): 127-129.
[24] Shah SR, Young S, Goldman JL, et al.A composite critical-size rabbit mandibular defect for evaluation of craniofacial tissue regeneration[J]. Nat Protoc, 2016, 11(10): 1989-2009.
[25] Bobarnac Dogaru GL, Juneja SC, Shokrani A, et al.The role of Hedgehog-responsive fibroblasts in facial nerve regeneration[J]. Exp Neurol, 2018, 303: 72-79.
[26] Zheng M, Duan J, He Z, et al.Transplantation of bone marrow stromal stem cells overexpressing tropomyosin receptor kinase A for peripheral nerve repair[J]. Cytotherapy,2017,19(8): 916-926.

颌面部麻木的检测及其治疗进展

Detection and treatment progress of facial numbness

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