应用T2 mapping诊断关节软骨疾病研究进展

doi:10.19438/j.cjoms.2019.06.017

中国口腔颌面外科杂志 ›› 2019, Vol. 17 ›› Issue (6): 566-570.doi: 10.19438/j.cjoms.2019.06.017

应用T2 mapping诊断关节软骨疾病研究进展

毛懿, 陈旭卓, 张善勇

上海交通大学医学院附属第九人民医院·口腔医学院口腔外科,国家口腔疾病临床医学研究中心,上海市口腔医学重点实验室,上海市口腔医学研究所,上海 200011

收稿日期:2018-08-13 出版日期:2019-11-20 发布日期:2019-12-16
通讯作者: 张善勇,E-mail：zhangshanyong@126.com
作者简介:毛懿（1994）,男,硕士研究生,E-mail：394736444@qq.com
基金资助:
上海交通大学医工交叉项目（YG2016QN09）; 上海交通大学医工交叉青年项目（YG2017QN08, YG2017MS04）

Research progress of using T2 mapping to diagnose articular cartilage diseases

MAO Yi, CHEN Xu-zhuo, ZHANG Shan-yong

Department of Oral Surgery, Collage of Stomatology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine; National Clinical Research Center for Oral Disease, Shanghai Key Laboratory of Stomatology, Shanghai Research Institute of Stomatology. Shanghai 200011, China

Received:2018-08-13 Online:2019-11-20 Published:2019-12-16

摘要/Abstract

摘要： 关节软骨是关节的重要结构之一,在运动时传递机械应力,减少关节面间的摩擦力。软骨组织受损后很难自愈,因此早期诊断和治疗对其预后非常重要。T2 mapping是一种通过描述组织横向磁化衰减来反映组织特性的半定量分析的磁共振诊断技术,能较好地评价关节软骨的早期改变,具有很大的临床应用潜力。本文就T2-mapping的发展近况进行综述。

关键词: 关节软骨, T2 mapping, 早期诊断

Abstract: Articular cartilage is one of the most important articulates, which plays an role in transferring the mechanical stress when exercising and decreasing friction between joint surfaces. Due to the lack of blood supply for articular tissue, injuries after articulate damage are difficult for self-healing. Thus, early diagnosis and treatment are necessary for articular damages. As a noninvasive diagnosis method in videography, nuclear magnetic resonance(NMR) is of vital importance in diagnosing articular injuries. T2-mapping enables the evaluation of early change of the articular cartilage by describing the transverse magnetization attenuation to reflect the semi-quantitative analysis of tissue character and has clinical potentials. This article was aimed to review the recent development of T2-mapping in diagnosis of articular cartilage diseases.

Key words: Articular cartilage, T2 mapping, Early diagnosis

中图分类号:

R782.6

毛懿, 陈旭卓, 张善勇. 应用T2 mapping诊断关节软骨疾病研究进展[J]. 中国口腔颌面外科杂志, 2019, 17(6): 566-570.

MAO Yi, CHEN Xu-zhuo, ZHANG Shan-yong. Research progress of using T2 mapping to diagnose articular cartilage diseases[J]. China J Oral Maxillofac Surg, 2019, 17(6): 566-570.

参考文献

[1] Brittberg M, Gomoll AH, Canseco JA, et al.Cartilage repair in the degenerative ageing knee[J]. Acta Orthop, 2016, 87(363): 26-38.
[2] Kreuz PC, Steinwachs MR, Erggelet C, et al.Results after microfracture of full-thickness chondral defects in different compartments in the knee[J]. Osteoarthritis Cartilage, 2006, 14(11): 1119-1125.
[3] Chubinskaya S, Haudenschild D, Gasser S, et al.Articular cartilage injury and potential remedies[J]. J Orthop Trauma, 2015, 29(Suppl 12): S47-52.
[4] 武淑锋. 膝半月板和关节软骨损伤CT与MRI诊断价值对比[J]. 影像研究与医学应用, 2018, 28(1): 82-83.
[5] 林海, 覃静. CT和MRI诊断膝半月板和关节软骨损伤的对比分析[J]. 中国CT和MRI杂志, 2015, 13(2): 88-89, 94.
[6] Li H, Tao H, Hua Y, et al.Quantitative magnetic resonance imaging assessment of cartilage status: a comparison between young men with and without anterior cruciate ligament reconstruction[J]. Arthroscopy, 2013, 29(12): 2012-2019.
[7] Tao H, Shang X, Lu R, et al.Quantitative magnetic resonance imaging (MRI) evaluation of cartilage repair afer microfracture (MF) treatment for adult unstable osteochondritis dissecans (OCD) in the ankle: correlations with clinical outcome[J]. Eur Radiol, 2014, 24(8): 1758-1767.
[8] Stahl R, Luke A, Li X, et al.T1ρ, T2 and focal knee cartilage abnormalities in physically active and sedentary healthy subjects versus early OA patients-a 3.0-Tesla MRI study[J]. Eur Radiol, 2009, 19(1): 132-143.
[9] Blumenkrantz G, Stahl R, Carballido-Gamio J, et al.The feasibility of characterizing the spatial distribution of cartilage T2 using texture analysis[J]. Osteoarthritis Cartilage, 2008, 16(5): 584-590.
[10] Mosher TJ, Dardzinski BJ.Cartilage MRI T2 relaxation time mapping: overview and applications[J]. Semin Musculoskelet Radiol, 2004, 8(4): 355-368.
[11] Kang Y, Chol JA.T2 mapping of articular cartilage of the glenohumeral joint at 3.0 T in healthy volunteers: a feasibility study[J]. Skeletal Radiol, 2016, 45(7): 915-920.
[12] Mosher TJ, Smith H, Dardzinski BJ, et al.MR imaging and T2 mapping of femoral cartilage: in vivo determination of the magic angle effect[J]. AJR Am J Roentgenol, 2001, 177(3): 665-669.
[13] 康思宁, 刘强. 骨关节炎病理过程与关节软骨特性的改变[J]. 中华关节外科杂志(电子版), 2007, 1(4): 275-278.
[14] 吴艳, 曾旭文, 梁治平, 等. T2 mapping评价关节软骨损伤及修复的研究进展[J].生物医学工程与临床, 2015, 19(2): 208-211.
[15] Kim HK, Horn P, Dardzinski BJ, et al.T2 relaxation time mapping of the cartilage cap of osteochondromas[J]. Korean J Radiol, 2016, 17(1): 159-165.
[16] Chen M, Qiu L, Shen S, et al.The influences of walking, running and stair activity on knee articular cartilage: Quantitative MRI using T1ρ and T2 mapping[J]. PLoS One, 2017, 12(11): e0187008
[17] Van Rossom S, Smith CR, Zevenbergen L, et al.Knee cartilage thickness, T1ρ and T2 relaxation time are related to articular cartilage loading in healthy adults[J]. PLoS One, 2017, 12(1): e0170002
[18] Matzat SJ, McWalter EJ, Kogan F, et al. T2 Relaxation time quantitation differs between pulse sequences in articular cartilage[J]. J Magn Reson Imaging, 2015, 42(1): 105-113.
[19] Yu A, Heilmeier U, Kretzschmar M, et al.Racial differencesin biochemical knee cartilage composition between African-American and Caucasian-American women with 3 T MR-based T2 relaxation time measurements-data from the Osteoarthritis Initiative[J]. Osteoarthritis Cartilage, 2015, 23(9): 1595-1604.
[20] Juras V, Zbyň Š, Mlynarik V, et al.The compositional difference between ankle and knee cartilage demonstrated by T2 mapping at 7 Tesla MR[J]. Eur J Radiol, 2016, 85(4): 771-777.
[21] Juras V, Bohndorf K, Heule R, et al.A comparison of multi-echo spinecho and triple-echo steady-state T2 mapping for in vivo evaluation of articular cartilage[J]. Eur J Radiol, 2016, 26(6): 1905-1912.
[22] 樊子健, 吴丽萍, 任有忠, 等. 3.0 T磁共振T2-Mapping、3D-FSE-Cube与常规序列对膝关节软骨损伤分级对比分析[J]. 磁共振成像, 2017, 8(9): 675-680.
[23] 崔倩. T2 mapping伪彩图及T2值对髌软骨损伤的诊断价值研究[D]. 大连: 大连医科大学, 2013.
[24] Teng HL, Pedoia V, Link TM, et al.Local associations between knee cartilage T1ρ and T2 relaxation times and patellofemoral joint stress during walking: A voxel-based relaxometry analysis[J]. Knee, 2018, 25(3): 406-416.
[25] Hada S, Ishijima M, Kaneko H, et al.Association of medial meniscal extrusion with medial tibial osteophyte distance detected by T2 mapping MRI in patients with early-stage knee osteoarthritis[J]. Arthritis Res Ther, 2017, 19(1): 201.
[26] Tao HY, Qiao Y, Hu YW, et al.Quantitative T2-Mapping and T2*-mapping evaluation of changes in cartilage matrix after acute anterior cruciate ligament rupture and the correlation between the results of both methods[J]. Biomed Res Int, 2018, 2018: 7985672.
[27] Kim CW, Hosseini A, Lin L, et al.Quantitative analysis of T2 relaxation times of the patellofemoral joint cartilage 3 years after anterior cruciate ligament reconstruction[J]. J Orthop Translat, 2018, 12(1): 85-92.
[28] Murakami K, Arai Y, Ikoma K, et al.Total resection of any segment of the lateral meniscus may cause early cartilage degeneration[J]. Medicine (Baltimore), 2018, 97(23): e11011.
[29] Wang W, Hou J, Lv D, et al.Multimodal quantitative magnetic resonance imaging for lumbar intervertebral discdegeneration[J]. Exp Ther Med, 2017, 14(3): 2078-2084.
[30] Yoon MA, Hong SJ, Kang CH, et al.T1ρ and T2 mapping of lumbar intervertebral disc: correlation with degeneration and morphologic changes in different disc regions[J]. Magn Reson Imaging, 2016, 34(7): 932-939.
[31] Messner A, Stelzeneder D, Trattnig S, et al.Does T2 mapping of the posterior annulus fibrosus indicate the presence of lumbarintervertebral disc herniation? A 3.0 Tesla magnetic resonance study[J]. Eur Spine J, 2017, 26(3): 877-883.
[32] Pachowsky ML, Kleyer A, Wagner L, et al.Quantitative T2 mapping shows increased degeneration in adjacent intervertebraldiscs following kyphoplasty[J]. Cartilage, 2018, 1: 1947603518758434.
[33] Kang Y, Choi JA.T2 mapping of articular cartilage of the glenohumeral joint at 3.0 T in healthy volunteers: a feasibility study[J]. Skeletal Radiol, 2016, 45(7): 915-920.
[34] Lee SY, Park HJ, Kwon HJ, et al.T2 relaxation times of the glenohumeral joint at 3.0 T MRI in patients with and without primary and secondary osteoarthritis[J]. Acta Radiol, 2015, 56(11): 1388-1395.
[35] Albano D, Chianca V, Cuocolo R, et al.T2-mapping of the sacroiliac joints at 1.5 Tesla: a feasibility and reproducibility study[J]. Skeletal Radiol, 2018, 47(12): 1691-1696.
[36] Shoji T, Yamasaki T, Izumi S, et al.Evaluation of articular cartilage following rotational acetabular osteotomy for hip dysplasia using T2 mapping MRI[J]. Skeletal Radiol, 2018, 47(11): 1467-1474.
[37] Karmazyn B, Lin C, Persohn SA, et al.Feasibility of mapping T2 relaxation time in the pediatric metacarpal head with a 3-T MRI system[J]. AJR Am J Roentgenol, 2012, 198(6): W602-604.
[38] Kakimoto N, Shimamoto H, Chindasombatjaroen J, et al.Comparison of the T2 relaxation time of the temporomandibular joint articular disk between patients with temporomandibular disorders and asymptomatic volunteers[J]. AJNR Am J Neuroradiol, 2014, 35(7): 1412-1417.
[39] Behzadi C, Maas KJ, Welsch G, et al.Quantitative T2* relaxation time analysis of articular cartilage of the tibiotalar jointin professional football players and healthy volunteers at 3T MRI[J]. J Magn Reson Imaging, 2018, 47(2): 372-379.

应用T2 mapping诊断关节软骨疾病研究进展

Research progress of using T2 mapping to diagnose articular cartilage diseases

PDF (PC)

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 1

编辑推荐

Metrics

本文评价