China Journal of Oral and Maxillofacial Surgery ›› 2022, Vol. 20 ›› Issue (2): 202-205.doi: 10.19438/j.cjoms.2022.02.019

• Case Reports • Previous Articles     Next Articles

Metastatic small cell neuroendocrine carcinoma of tongue base: a case report, review

QIAN Min1,2, SHEN Yue-hong2, WU Li2, YANG Hong-yu1,2   

  1. 1. School of Clinical Medicine, Peking University Shenzhen Hospital, Anhui Medical University. Hefei 230032, Anhui Province;
    2. Department of Oral and Maxillofacial Surgery, Peking University Shenzhen Hospital. Shenzhen 518036, Guangdong Province, China
  • Received:2021-09-27 Revised:2021-11-15 Online:2022-03-20 Published:2022-03-20

Abstract: Extra-pulmonary small cell neuroendocrine carcinoma is rare and very highly malignant disease, which is generally diagnosed at an advanced stage and has a poor prognosis. The diagnosis is based essentially on the morphological appearance of the tumor, confirmed by immunocytochemical features. We here contributed by reporting a case of tongue metastasis from primary cervical small cell neuroendocrine carcinoma and reviewed the current literatures about its diagnosis and treatment.

Key words: Small cell carcinoma, Neuroendocrine carcinoma, Immunohistochemistry

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