中国口腔颌面外科杂志

中国口腔颌面外科杂志 ›› 2026, Vol. 24 ›› Issue (3): 218-222.doi: 10.19438/j.cjoms.2026.03.003

• 论著 • 上一篇    下一篇

3D打印内置支架引导下显微血管吻合的实验研究

李文浩1, 赵雪1, 韩少伟1, 李亚辉1, 黄旭2, 陈传俊3   

  1. 1.蚌埠医科大学口腔医学院,安徽 蚌埠 233030;
    2.皖南医学院 研究生院,安徽 芜湖 241002;
    3.中国科学技术大学附属第一医院 口腔颌面外科,安徽 合肥 230001
  • 收稿日期:2025-07-30 修回日期:2025-10-09 出版日期:2026-05-20 发布日期:2026-06-04
  • 通讯作者: 陈传俊,E-mail: ccj6318@sina.com
  • 作者简介:李文浩（2000—）,男,硕士研究生,E-mail: 2931268682@qq.com
  • 基金资助:
    中央高校基本科研业务费专项资金资助（WK9110000146）

Experimental study on microsurgical vascular anastomosis guided by 3D-printed intravascular stent

Li Wenhao1, Zhao Xue1, Han Shaowei1, Li Yahui1, Huang Xu2, Chen Chuanjun3   

  1. 1. School of Stomatology, Bengbu Medical University. Bengbu 233030;
    2. Graduate School, Wannan Medical College. Wuhu 241002;
    3. Department of Oral and Maxillofacial Surgery, First Affiliated Hospital of University of Science and Technology of China. Hefei 230001, Anhui Province, China
  • Received:2025-07-30 Revised:2025-10-09 Online:2026-05-20 Published:2026-06-04

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摘要： 目的: 探讨3D打印内置支架辅助显微血管吻合的可行性。方法: 选取20只健康新西兰大白兔,采用自身对照设计。暴露并横断双侧颈总动脉,右侧行传统显微间断缝合（对照组）,左侧置入3D打印纯钛内置支架后吻合（实验组）。记录两组吻合时间、术后即刻及14天血管通畅率,统计吻合口漏血发生率。结果: 实验组吻合时间为（21.97±2.99） min,显著短于对照组的（27.68±4.27） min（P<0.05）。实验组即刻通畅率为100%（20/20）,对照组为90%（18/20）;实验组术后14天通畅率为95%（19/20）,对照组为75%（15/20）,两组通畅率差异无统计学意义（P>0.05）。实验组漏血率为5%（1/20）,显著低于对照组的35%（7/20,P<0.05）。结论: 3D打印纯钛内置支架可通过机械支撑与缝合引导,显著缩短显微血管吻合时间、降低漏血率,且不影响血管通畅性,同时减少对术者精细缝合技能的依赖,可为显微血管吻合提供新型辅助方案。

关键词: 显微血管吻合, 血管内支架, 3D打印, 显微外科

Abstract: PURPOSE: To explore the feasibility of 3D-printed internal stents in assisting microsurgical vascular anastomosis. METHODS: Twenty healthy New Zealand white rabbits were selected and subjected to a self-controlled design. The bilateral common carotid arteries were exposed and transected: the right side underwent traditional interrupted suture (control group), while the left side was anastomosed after implantation of a 3D-printed pure titanium internal stent (experimental group). The anastomosis time, immediate postoperative and 14-day postoperative vascular patency rates were recorded, and the incidence of anastomotic bleeding was statistically analyzed. RESULTS: The anastomosis time of the experimental group was (21.97±2.99) min, which was significantly shorter than that of the control group [(27.68±4.27) min, P<0.05]. The immediate postoperative patency rate was 100%(20/20) in the experimental group and 90%(18/20) in the control group; the 14-day postoperative patency rate was 95%(19/20) in the experimental group and 75%(15/20) in the control group, with no statistically significant difference in patency rate between the two groups (P>0.05). The bleeding rate of the experimental group was 5% (1/20), which was significantly lower than that of the control group (35%, 7/20, P<0.05). CONCLUSIONS: 3D-printed pure titanium internal stents can significantly shorten the microsurgical vascular anastomosis time and reduce the bleeding rate through mechanical support and suture guidance, without affecting vascular patency. At the same time, it reduces the reliance on the surgeon's fine suture skills, providing a new auxiliary solution for microsurgical vascular anastomosis.

Key words: Microsurgical vascular anastomosis, Intravascular stent, 3D printing, Microsurgery

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