婴儿腮腺成涎细胞瘤手术治疗的初步探讨

中国口腔颌面外科杂志 ›› 2015, Vol. 13 ›› Issue (2): 167-170.

婴儿腮腺成涎细胞瘤手术治疗的初步探讨

王友元, 张大明, 范松, 王磊, 黄志权, 杨朝晖, 李劲松, 陈伟良

中山大学孙逸仙纪念医院口腔颌面外科,广东广州 510120

收稿日期:2014-02-26 修回日期:2014-04-08 出版日期:2015-03-20 发布日期:2015-04-23
通讯作者: 陈伟良,Tel: 020-81332429,Fax: 020-81332853,E-mail:drchen@vip.163.com
作者简介:王友元（1981-）,男,博士,主治医师, E-mail：sumswangyy@163.com

Surgical excision of sialoblastoma in the parotid gland in newborn

WANG You-yuan, ZHANG Da-ming, FAN Song, WANG Lei, HUANG Zhi-quan, YANG Zhao-hui, LI Jin-song, CHEN Wei-liang

Department of Oral and Maxillofacial Surgery, Sun Yet-sen Memorial Hospital, Sun Yat-sen University. Guangzhou 510120, Guangdong Province, China

Received:2014-02-26 Revised:2014-04-08 Online:2015-03-20 Published:2015-04-23

摘要/Abstract

摘要： 目的: 评价婴儿腮腺成涎细胞瘤手术治疗的疗效。方法: 回顾分析我科行手术治疗的3例婴儿腮腺成涎细胞瘤,肿瘤大小为5 cm×4 cm~8 cm×5 cm,肿瘤可完整切除并保存面神经。结果: 所有患儿均未出现并发症,中位随访期为34个月,未见肿瘤复发。结论: 手术治疗婴儿腮腺成涎细胞瘤是安全有效的方法。

关键词: 成涎细胞瘤, 腮腺肿瘤, 婴幼儿, 头颈部

Abstract: PURPOSE: To evaluate the outcome of surgical excision of sialoblastoma in the parotid gland in newborn. METHODS: This was a retrospective review of 3 pediatric patients with sialoblastoma in the parotid gland undergoing surgical resection. All patients were newborn boys. The lesions ranged from 5 cm×5 cm to 8 cm×5 cm in size. The tumor was resected en bloc, and the facial nerve was preserved. RESULTS: No complications occurred. The mean follow-up period was 34 months; no patients had recurrent lesions. CONCLUSIONS: Surgical resection of sialoblastoma in the parotid gland in newborn is efficient and safe.

Key words: Sialoblastoma, Parotid gland tumor, Infant, Head and neck

中图分类号:

R782.2

王友元, 张大明, 范松, 王磊, 黄志权, 杨朝晖, 李劲松, 陈伟良. 婴儿腮腺成涎细胞瘤手术治疗的初步探讨[J]. 中国口腔颌面外科杂志, 2015, 13(2): 167-170.

WANG You-yuan, ZHANG Da-ming, FAN Song, WANG Lei, HUANG Zhi-quan, YANG Zhao-hui, LI Jin-song, CHEN Wei-liang. Surgical excision of sialoblastoma in the parotid gland in newborn[J]. China J Oral Maxillofac Surg, 2015, 13(2): 167-170.

参考文献

[1] Saribeyoglu ET, Devecioglu O, Karakas Z, et al. How to manage an unresectable or recurrent sialoblastoma [J]. Pediatr Blood Cancer, 2010, 55(2): 374-376.
[2] Barnes L, Eveson JW, Reichart P, et al. Pathology and genetics of head and neck tumours [C]// Kleihues P, Sobin LH. World Health Organization classification of tumours [M]. 3rd Ed. Lyon： IARC Press, 2005: 253.
[3] Vawter GF, Tefft M. Congenital tumours of the parotid gland [J]. Arch Pathol, 1966, 2(3): 242-245.
[4] Taylor GP. Congenital epithelial tumor of the parotid-sialoblastoma [J]. Pediatr Pathol, 1988, 8(4): 447-452.
[5] Hsueh C, Gonzalez-Crussi F. Sialoblastoma: a case report and review of the literature on congenital epithelial tumors of salivary gland origin [J]. Pediatr Pathol, 1992, 12(2): 205-214.
[6] Vidyadhar M, Amanda C, Thuan Q, et al. Sialoblastoma [J]. J Pediatr Surg, 2008, 43(10): e11-13.
[7] Saffari Y, Blei F, Warren SM, et al. Congenital minor salivary gland sialoblastoma: a case report and review of the literature [J]. Fetal Pediatr Pathol, 2011, 30(1): 32-39.
[8] Ersoz S, Turgutalp H, Cobanoglu U, et al. Sialoblastoma in the parotid gland: a case report[J]. Pediatr Int,2010, 52(4):670-672.
[9] Shan XF, Cai ZG, Zhang JG, et al. Management of sialoblastoma with surgery and brachytherapy[J]. Pediatr Blood Cancer,2010,55(7): 1427-1430.
[10] Prigent M, Teissier N, Peuchmaur M, et al. Sialoblastoma of salivary glands in children: chemotherapy should be discussed as an alternative to mutilating surgery [J]. Int J Pediatr Otorhinolaryngol, 2010, 74(8): 942-945.
[11] Kattoor J, Baisakh MR, Mathew A, et al. Sialoblastoma: a rare salivary gland neoplasm [J]. Indian J Cancer, 2010, 47(2): 219-220.
[12] Patil DT, Chou PM. Sialoblastoma: utility of Ki-67 and p53 as a prognostic tool and review of literature [J]. Pediatr Dev Pathol, 2010, 13(1): 32-38.
[13] Mertens F, Wahlberg P, Domanski HA. Clonal chromosome aberrations in a sialoblastoma [J]. Cancer Genet Cytogenet, 2009, 189(1): 68-69.
[14] Marucci DD, Lawson K, Harper J, et al. Sialoblastoma arising in ectopic salivary gland tissue[J]. J Plast Reconstr Aesthet Surg, 2009, 62(8): e241-246.
[15] Stones DK, Jansen JC, Griessel D. Sialoblastoma and hepatoblastoma in a newborn infant[J]. Pediatr Blood Cancer, 2009, 52(7): 883-885.
[16] Siddiqi H, Solomon MP, Haller JO. Sialoblastoma and hepatoblastoma in a neonate[J]. Pediatr Radiol, 2000, 30(5): 349-351.
[17] Farooqi KM, Kessel R, Brandwein-Gensler M, et al. Sialoblastoma-long-term follow-up and remission for a rare salivary malignancy [J]. Rare Tumors, 2011, 3(2): e13.
[18] Batsakis JG, Mackay B, Ryka AF, et al. Perinatal salivary gland tumours (Embryomas) [J]. J Laryngol Otol, 1988, 102(11): 1007-1011.
[19] Cristofaro M, Giudice A, Amentea M, et al. Diagnostic and therapeutic approach to a sialoblastoma of the submandibular gland: a case report [J]. J Oral Maxillofac Surg, 2008, 66(1): 123-126.
[20] Papaioannou G, Sebire NJ, McHugh K. Imaging of the unusual pediatric ‘blastomas’ [J]. Cancer Imaging, 2009, 9: 1-11.
[21] Yekeler E, Dursun M, Gun F, et al. Sialoblastoma: MRI findings [J]. Pediatr Radiol, 2004, 34(12): 1005-1007.