中国口腔颌面外科杂志 ›› 2024, Vol. 22 ›› Issue (5): 505-509.doi: 10.19438/j.cjoms.2024.05.016

• 综述 • 上一篇    下一篇

钛合金支架及其表面处理技术研究进展

陶文昊1, 田刚1, 韩煦1, 祝迎春2,*, 徐晓刚1,*   

  1. 1.海军军医大学第一附属医院 口腔科,上海 200433;
    2.中国科学院上海硅酸盐研究所 中国科学院特种无机涂层重点实验室,上海 200050
  • 收稿日期:2023-12-07 修回日期:2024-01-15 出版日期:2024-09-20 发布日期:2024-09-29
  • 通讯作者: 祝迎春,E-mail: yzhu@mail.sic.ac.cn;徐晓刚,E-mail: xxgsmmu@sina.com。*共同通信作者
  • 作者简介:陶文昊(1998-),男,在读硕士研究生,E-mail: 854260754@qq.com

Research progress of titanium alloy scaffolds and its surface modification technology

TAO Wen-hao1, TIAN Gang1, HAN Xu1, ZHU Ying-chun2, XU Xiao-gang1   

  1. 1. Department of Stomatology, First Affiliated Hospital of Naval Medical University. Shanghai 200433;
    2. Key Laboratory of Inorganic Coating Materials of Chinese Academy of Sciences, Shanghai Institute of Ceramics, Chinese Academy of Sciences. Shanghai 200050, China
  • Received:2023-12-07 Revised:2024-01-15 Online:2024-09-20 Published:2024-09-29

摘要: 3D打印制造出的Ti-6Al-4V多孔支架相比传统的钛合金支架,力学性能更加接近天然骨组织,具有很好的生物相容性,有望成为骨缺损修复的理想材料。为提升钛合金的生物性能,各种表面处理技术应运而生,这些处理技术可分为涂层法和非涂层法,而不同的表面处理技术各有优劣,本文就钛合金支架及其表面处理技术的研究进展进行综述。

关键词: 3D打印, 多孔钛合金, 聚多巴胺, 羟基磷灰石, 纤维蛋白原, Ⅰ型胶原蛋白, 成骨, 软组织封闭

Abstract: Compared with traditional titanium alloy scaffolds, the mechanical properties of Ti-6Al-4V porous scaffolds fabricated by 3D printing are closer to natural bone tissue and have good biocompatibility, which is expected to become an ideal material for bone defect repair. In order to improve the biological properties of titanium alloy, various surface treatment technologies emerge as the times require. These treatment technologies can be divided into coating and non-coating method, and different surface treatment technologies have their own advantages and disadvantages. This paper reviewed the research progress of titanium alloy scaffolds and their surface treatment technologies.

Key words: 3D printing, Porous titanium alloy, Polydopamine, Hydroxyapatite, Fibrinogen, CollageⅠ, Osteogenesis, Soft tissue sealing

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