正颌患者术后恶心、呕吐影响因素的meta分析

doi:10.19438/j.cjoms.2025.04.014

摘要/Abstract

摘要： 目的：探讨正颌患者术后恶心、呕吐（postoperative nausea and vomiting,PONV）的影响因素。方法：检索中国知网、万方数据库、维普网、中国生物医学数据库、PubMed、Web of Science、Cochrane Library、Embase和SpringerLink数据库,查找正颌患者PONV影响因素分析的相关研究,采用RevMan5.3软件进行数据分析。根据异质性检验结果,采用固定效应模型或随机效应模型进行分析,并对结果进行敏感性分析和发表偏倚评价。结果：共纳入7篇文献,研究对象共2 280例。有4个因素的合并比值比（OR值）有显著意义。结果显示,性别[OR=1.62,95%CI (1.12,2.33)]、手术类型[OR=1.77,95%CI(1.41,2.22)]、术后使用阿片类药物[OR=1.99,95%CI(1.19,3.33)]、PONV史[OR=2.98,95%CI(1.66,5.35)]是正颌患者PONV的影响因素。结论：女性、接受双颌正颌手术、术后使用阿片类药物、有PONV史可能是正颌患者PONV的危险因素。

关键词: 正颌手术, 术后恶心、呕吐, 影响因素, Meta分析

Abstract: PURPOSE: To explore the influencing factors of postoperative nausea and vomiting(PONV) in orthognathic patients. METHODS: CNKI, Wanfang Database, Weipu.com, China Biomedical Database, PubMed, Web of Science, Cochrane Library, Embase and SpringerLink databases were searched to find relevant studies on the analysis of PONV influencing factors in orthognathus patients. The data were analyzed by RevMan5.3 software, the results of heterogeneity test were analyzed by fixed effects model or random effects model, and sensitivity analysis and publication bias evaluation were also conducted. RESULTS: A total of 7 literatures were included, with a total of 2280 subjects. The combined OR values of four factors were significant. The results showed gender [OR=1.62, 95%CI(1.12,2.33)], type of surgery [OR=1.77, 95%CI(1.41,2.22)], postoperative opioid use [OR=1.99, 95%CI(1.19,3.33)], PONV history [OR=2.98, 95%CI(1.66,5.35)] was the influencing factor of PONV in orthognathic patients. CONCLUSIONS: Female, bimaxillary orthognathic surgery, postoperative opioid use, and history of PONV were risk factors for orthognathic patients.

Key words: Orthognathic surgery, PONV, Influencing factors, Meta analysis

中图分类号:

R782.2

蒋美平, 王增香, 吴颖, 李婷, 黄茜. 正颌患者术后恶心、呕吐影响因素的meta分析[J]. 中国口腔颌面外科杂志, 2025, 23(4): 401-405.

Jiang Meiping, Wang Zengxiang, Wu Ying, Li Ting, Huang Qian. Influencing factors of postoperative nausea and vomiting in orthognathic surgery patients: a meta-analysis[J]. China J Oral Maxillofac Surg, 2025, 23(4): 401-405.

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