125I放射性粒子植入术后口腔癌患者生存质量现状及影响因素分析

doi:10.19438/j.cjoms.2025.03.009

摘要/Abstract

摘要： 目的：探讨¹²⁵I放射性粒子植入术后口腔癌患者的生存质量现状,并分析其影响因素。方法：选择2022年6月—2024年3月在山东省立医院接受¹²⁵I放射性粒子治疗的266例口腔癌患者为研究对象。应用一般资料调查表、华盛顿大学生存质量问卷（UW-QOL）、恐惧疾病进展简化量表（FoP-Q-SF）、医学应对方式问卷（MCMQ）分析研究对象的生存质量及影响因素。采用SPSS 25.0软件对数据进行统计学分析。结果：¹²⁵I粒子植入术后,口腔癌患者生存质量总分为（104.11±16.40）分,处于中上水平;恐惧疾病进展总分为（28.19±3.16）分,其中86例（32.33%）恐惧疾病进展总分≥34分（临床水平）。266例患者医学应对方式问卷中,面对维度平均值为（17.81±3.138）分,回避维度平均分为（14.41±3.516）分,屈服维度平均值为（8.19±3.26）分。回归分析结果显示,屈服应对、年龄、恐惧疾病进展生理维度、性别、居住地、疼痛进入回归方程,共解释生存质量变异量的48.3%。结论：¹²⁵I粒子植入术后口腔癌患者生存质量分值处于中上等水平,临床医护人员应指导¹²⁵I粒子植入术后口腔癌患者采取积极的应对方式,并结合患者年龄、性别、恐惧疾病进展程度、居住地、疼痛现状等特点制定个性化护理措施,提高生存质量。

关键词: 口腔癌, ¹²⁵I放射性粒子, 生存质量, 影响因素

Abstract: PURPOSE: To investigate the status of quality of life in patients with oral cancer after ¹²⁵I radioactive seed implantation, and to analyze its influencing factors. METHODS: A total of 266 patients with oral cancer who received ¹²⁵I radioactive seed implantation in Shandong Provincial Hospital from June 2022 to March 2024 were selected as the study objects. General information questionnaire, University of Washington Quality of Life Questionnaire (UW-QOL), Fear of Progression Questionnaire Short Form (FoP-Q-SF), and Medical Coping Modes Questionnaire (MCMQ) were used to analyze the quality of life of the subjects and its influencing factors. SPSS 25.0 software was used for data analysis. RESULTS: The score of quality of life in oral cancer patients after ¹²⁵I radioactive seed implantation was (104.11±16.40), which was above the medium level. The total score of fear of disease progression was (28.19±3.16), and 86 patients(32.33%) were≥34 (clinical level). The scores of 266 patients with oral cancer in terms of medical coping style were confrontation(17.81±3.138), avoiding dimension(14.41±3.516) and surrender (8.19±3.26). The results of regression analysis showed that the surrender modes, age, physiological dimension of fear of cancer recurrence, gender, residence, pain status were the influencing factors that entered the regression equation,explaining 48.3% of the variance. CONCLUSIONS: The quality of life score of oral cancer patients after ¹²⁵I radioactive seed implantation is in the upper level. Medical staff should instruct oral cancer patients to take a positive approach to disease management after ¹²⁵I seed implantation, and combined with the patient's age, gender, fear of recurrence, residence, pain status and other characteristics to develop personalized nursing measures, so as to improve the quality of life.

Key words: Oral cancer, ¹²⁵I radioactive seeds, Quality of life, Influencing factors

中图分类号:

R739.8

赵延芳, 魏银萍, 王维香, 祁惟遥, 黄圣运, 侯亚丽. ¹²⁵I放射性粒子植入术后口腔癌患者生存质量现状及影响因素分析[J]. 中国口腔颌面外科杂志, 2025, 23(3): 264-270.

Zhao Yanfang, Wei Yinping, Wang Weixiang, Qi Weiyao, Huang Shengyun, Hou Yali. Analysis and influencing factors of quality of life in patients with oral cancer after ¹²⁵I radioactive seed implantation[J]. China J Oral Maxillofac Surg, 2025, 23(3): 264-270.

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¹²⁵I放射性粒子植入术后口腔癌患者生存质量现状及影响因素分析

Analysis and influencing factors of quality of life in patients with oral cancer after ¹²⁵I radioactive seed implantation

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