聚多卡醇治疗血管瘤及脉管畸形研究进展

doi:10.19438/j.cjoms.2020.01.016

摘要/Abstract

摘要： 血管瘤与脉管畸形是临床常见病,头颈部发病率约40%~60%,不仅造成颜面部畸形,影响美观,还可影响吞咽、呼吸等生理功能,严重者可能因感染、溃疡、压迫呼吸道等危及生命。复杂血管瘤与脉管畸形的治疗,一直是临床上面临的难题与挑战,目前主要治疗方法有手术切除、硬化治疗、激光治疗、介入治疗等,其中硬化治疗不仅在静脉畸形、淋巴管畸形等疾病中得到广泛应用,而且逐渐应用于血管瘤、化脓性肉芽肿等疾病的治疗。作为硬化治疗的药物—硬化剂,聚多卡醇在临床上的应用越来越广泛。本文从硬化原理、临床应用、安全性及有效性等方面,对聚多卡醇治疗血管瘤及脉管畸形的相关背景及研究进展做一综述。

关键词: 聚多卡醇, 硬化治疗, 泡沫硬化剂, 血管瘤, 脉管畸形

Abstract: Hemangiomas and vascular malformations are common diseases with a prevalence about 40%-60% in head and neck, which can cause significant aesthetic and functional problem, even leading to death. The treatment of complex hemangiomas and vascular malformations remain a global challenge. The current treatment strategy mainly include surgical resection, sclerotherapy, laser therapy and endovascular interventional therapy. As an effective method for venous malformations and lymphatic malformations, sclerotherapy has been gradually used in treating hemangiomas and pyogenic granuloma. Polidocanol is one of the sclerosing agents widely used worldwide. This article reviewed the background and up-to-date advances of polidocanol in treating hemangiomas and vascular malformations.

Key words: Polidocanol, Sclerotherapy, Foam scleroagent, Hemangiomas, Vascular malformations

中图分类号:

R739.8

张涵恕, 刘少华, 郑家伟. 聚多卡醇治疗血管瘤及脉管畸形研究进展[J]. 中国口腔颌面外科杂志, 2020, 18(1): 77-81.

ZHANG Han-shu, LIU Shao-hua, ZHENG Jia-wei. Polidocanol sclerotherapy for hemangiomas and vascular malformations: an up-to-date advance[J]. China J Oral Maxillofac Surg, 2020, 18(1): 77-81.

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