数字医学辅助下创伤性骨化肌炎的手术治疗：1例报告及文献复习

doi:10.19438/j.cjoms.2017.02.009

中国口腔颌面外科杂志 ›› 2017, Vol. 15 ›› Issue (2): 142-146.doi: 10.19438/j.cjoms.2017.02.009

数字医学辅助下创伤性骨化肌炎的手术治疗：1例报告及文献复习

王翔宇, 郑吉驷, 张善勇^*, 杨驰^*

上海交通大学医学院附属第九人民医院·口腔医学院口腔外科,上海市口腔医学重点实验室,上海 200011

收稿日期:2016-03-09 出版日期:2017-03-20 发布日期:2017-04-13
通讯作者: 张善勇,E-mail: zhangshanyong@126.com;杨驰,E-mail: yangchi63@hotmail.com。*共同通信
作者简介:王翔宇（1992-）,男,在读硕士研究生,E-mail:wxy_eric@hotmail.com

Therapeutic effect of individualized template-guided ¹²⁵I seed implants for unresectable malignant salivary gland tumors

ZHENG Hao¹, YANG Xu-dong¹, Meng Jian²

1.Department of Oral and Maxillofacial Surgery, Nanjing Stomatological Hospital. Nanjing 210008;
2.Department of Stomatology, The Affiliated Xuzhou Hospital of Medical College of Southeast University. Xuzhou 221009, Jiangsu Province, China

Received:2016-03-09 Online:2017-03-20 Published:2017-04-13
Contact: 国家自然科学基金（81371168）; 上海市科学技术委员科研计划项目（14DZ2294300）

摘要/Abstract

Abstract: PURPOSE : To evaluate the short-term effect of individualized template guided 125I seed implants for advanced unresectable malignant salivary gland tumors, and explore its superiority. METHODS : Fourteen patients with histologically documented advanced unresectable malignant salivary gland tumors were treated by radioactive 125I seeds interstitial implantation under the aid of individualized template guide. The treatment response, distribution of seeds, local control rate and survival rate were evaluated and the adverse events observed. RUSULTS: The actuarial median number of 125I seeds treated was 43, and actuarial median D90,V100,V150 was 186.2 Gy, 98.2%, 43.4%, respectively; The average radiation dose received by the eyes and brain was 3.2 Gy, 32.5 Gy, respectively; The overall response rate was 78.3%. The patients were followed up for 15 to 28 months (median 23 months). The local control rate was 78.6%, and overall survival rate was 78.6%. No serious side radiotherapeutic effect was observed. CONCLUSION S: The method of individualized template-guided 125I seed implants for advanced unresectable malignant salivary gland tumors is feasible, minimally invasive, safe and easy to operate, which can be widely used in clinical practice.

Key words: Head and neck neoplasms, Adenogenous malignant tumor, ¹²⁵I seeds, Individualized template, Brachytherapy

中图分类号:

R782.4

王翔宇, 郑吉驷, 张善勇, 杨驰. 数字医学辅助下创伤性骨化肌炎的手术治疗：1例报告及文献复习[J]. 中国口腔颌面外科杂志, 2017, 15(2): 142-146.

ZHENG Hao, YANG Xu-dong, Meng Jian. Therapeutic effect of individualized template-guided ¹²⁵I seed implants for unresectable malignant salivary gland tumors[J]. China J Oral Maxillofac Surg, 2017, 15(2): 142-146.

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数字医学辅助下创伤性骨化肌炎的手术治疗：1例报告及文献复习

Therapeutic effect of individualized template-guided ¹²⁵I seed implants for unresectable malignant salivary gland tumors

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数字医学辅助下创伤性骨化肌炎的手术治疗：1例报告及文献复习

Therapeutic effect of individualized template-guided 125I seed implants for unresectable malignant salivary gland tumors

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Therapeutic effect of individualized template-guided ¹²⁵I seed implants for unresectable malignant salivary gland tumors