口腔疣状黄瘤1例报告及文献复习

doi:10.19438/j.cjoms.2026.02.016

中国口腔颌面外科杂志 ›› 2026, Vol. 24 ›› Issue (2): 196-199.doi: 10.19438/j.cjoms.2026.02.016

口腔疣状黄瘤1例报告及文献复习

邵禹^1,2, 于汶源¹, 徐勇³, 徐进³, 陈正岗^3,4

1.山东第二医科大学口腔医学院,山东潍坊 261053;
2.康复大学青岛医院（青岛市市立医院）口腔科,山东青岛 266011;
3.滨州医学院口腔医学院,山东烟台 264003;
4.滨州医学院附属烟台口腔医院,山东烟台 264000

收稿日期:2025-07-18 修回日期:2025-08-21 出版日期:2026-03-20 发布日期:2026-04-02
通讯作者: 陈正岗,E-mail：chenzhg1973@163.com
作者简介:邵禹（1997—）,男,在读硕士研究生,住院医师,E-mail: 1803250601@qq.com
基金资助:
山东省医药卫生科技项目（202308020420）;烟台市自然科学基金生物医药创新联合基金项目（ZR2025LZ057）;青岛市医药卫生科研指导项目（2023-WJZD164）

Oral verrucous xanthoma: a case report and literature review

Shao Yu^1,2, Yu Wenyuan¹, Xu Yong³, Xu Jin³, Chen Zhenggang^3,4

1. School of Stomatology, Shandong Second Medical University. Weifang 261053;
2. Department of Stomatology, Qingdao Hospital, University of Health and Rehabilitation Sciences (Qingdao Municipal Hospital). Qingdao 266011;
3. School of Stomatology, Binzhou Medical University. Yantai 264003;
4. The Affiliated Yantai Stomatological Hospital, Binzhou Medical University. Yantai 264000, Shandong Province, China

Received:2025-07-18 Revised:2025-08-21 Online:2026-03-20 Published:2026-04-02

摘要/Abstract

摘要： 疣状黄瘤（verruciform xanthoma,VX）是一种少见的皮肤黏膜良性病变,临床表现不典型,易误诊。一般只能通过组织病理检查确诊,其诊断标志是在延长的上皮钉突之间的结缔组织乳头中发现大量泡沫细胞聚集。本文报告1例左侧腭部疣状黄瘤,于当地医院就诊时被误诊为高分化牙龈癌,于本院切除后经组织病理学检查确诊为疣状黄瘤。本文结合相关文献进行复习,分析误诊原因,以减少或避免误诊发生。

关键词: 疣状黄瘤, 口腔肿瘤, 口腔黏膜病变

Abstract: Verruciform xanthoma (VX) is a rare benign lesion of the skin and mucous membranes with an atypical clinical presentation that makes it easy to misdiagnose. The diagnosis can usually only be confirmed by histopathology, and its diagnostic hallmark is the finding of large foam cell aggregates in connective tissue papillae between extended epithelial pegs. This paper reported a case of verrucous xanthoma of the left palate, which was misdiagnosed as highly differentiated gingival carcinoma during consultation at a local hospital, and was diagnosed as verrucous xanthoma after resection and histopathologic examination at our hospital. Combined with a review of relevant literature, this article discussed the causes of misdiagnosis, aiming to reduce or avoid such misdiagnoses in clinical practice.

Key words: Verrucous xanthoma, Oral tumor, Oral mucosal lesions

中图分类号:

R739.8

邵禹, 于汶源, 徐勇, 徐进, 陈正岗. 口腔疣状黄瘤1例报告及文献复习[J]. 中国口腔颌面外科杂志, 2026, 24(2): 196-199.

Shao Yu, Yu Wenyuan, Xu Yong, Xu Jin, Chen Zhenggang. Oral verrucous xanthoma: a case report and literature review[J]. China J Oral Maxillofac Surg, 2026, 24(2): 196-199.

参考文献

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口腔疣状黄瘤1例报告及文献复习

Oral verrucous xanthoma: a case report and literature review

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