颌面部原发性皮肤间变大细胞淋巴瘤1例报告及文献复习

doi:10.19438/j.cjoms.2021.04.019

摘要/Abstract

摘要： 原发性CD30⁺间变性大细胞淋巴瘤是一种少见的非霍奇金淋巴瘤,该病主要好发于 60岁左右,常发生于四肢和躯干,临床检查为质韧、边界清楚、结节状肿物。组织病理学检查显示皮下组织内有大量淋巴细胞,形态学结合免疫组织化学是诊断本病较为有效的方法。皮肤原发性病变临床少见,原发于颌面部者更为罕见。本文对临床上发现的1例原发于颌面部皮肤的间变大细胞淋巴瘤做一报告,并对相关文献进行复习。

关键词: 淋巴瘤, CD30⁺间变, 免疫组织化学

Abstract: Primary CD30 positive anaplastic large cell lymphoma is a rare non-Hodgkin's lymphoma. The disease mainly occurs around 60 years old, often in the limbs and trunk. Clinical examination often found tough, well demarcated nodular mass. Histopathological examination showed that a large number of lymphocytes are in the subcutaneous tissue. Morphology combined with immunohistochemical is more effective for diagnosis of this disease. Primary cutaneous ALCL is relatively rare, and primary anaplastic cell lymphoma occuring in the maxillofacial skin is much rare in clinic. In order to improve the diagnosis and treatment of the disease by oral and maxillofacial surgeons, this paper reported a case of ALCL in the maxillofacial skin and review the relevant literatures.

Key words: Lymphoma, CD30⁺ anaplasia, Immunohistochemistry

中图分类号:

R739.8

杨彩秀, 卜令学, 陈立强, 范存晖, 王双义. 颌面部原发性皮肤间变大细胞淋巴瘤1例报告及文献复习[J]. 中国口腔颌面外科杂志, 2021, 19(4): 380-384.

YANG Cai-xiu, BU Ling-xue, CHEN Li-qiang, FAN Cun-hui, WANG Shuang-yi. Primary facial CD30 positive anaplastic large cell lymphoma：report of one case and review of the literature[J]. China J Oral Maxillofac Surg, 2021, 19(4): 380-384.

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