中国口腔颌面外科杂志

中国口腔颌面外科杂志 ›› 2019, Vol. 17 ›› Issue (6): 481-485.doi: 10.19438/j.cjoms.2019.06.001

• 卫生健康事业发展70年巡礼专栏 • 上一篇    下一篇

2019年NCCN口腔口咽癌诊疗指南更新解读

尚伟1,2,*, 郑家伟3,*   

  1. 1.青岛大学附属医院 口腔颌面外科,山东 青岛 266003;
    2.青岛大学口腔医学院,山东 青岛 266003;
    3.上海交通大学医学院附属第九人民医院·口腔医学院 口腔颌面-头颈肿瘤科,上海 200011;
  • 收稿日期:2019-07-15 出版日期:2019-11-20 发布日期:2019-12-16
  • 通讯作者: 尚伟,E-mail：liweishang@126.com;郑家伟,E-mail：davidzhengjw@hotmail.com。*共同通信作者
  • 作者简介:尚伟（1963-）,男,教授,主任医师,博士研究生导师。

Interpretation of updated NCCN guidelines for diagnosis and treatment of oral and oropharyngeal cancer issued in 2019

SHANG Wei1,2, ZHENG Jia-wei3   

  1. 1.Department of Oral and Maxillofacial Surgery, the Affiliated Hospital of Qingdao University. Qingdao 266003;
    2. School of Stomatology, Qingdao University. Qingdao 266003, Shandong Province;
    3.Department of Oromaxillofacial Head and Neck Oncology, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine. Shanghai 200011, China
  • Received:2019-07-15 Online:2019-11-20 Published:2019-12-16

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摘要： 美国癌症联合委员会2017年第8版《AJCC肿瘤分期手册》出版,口腔及口咽癌TNM分期标准中新增侵袭深度（DOI）、淋巴结外扩展（ENE）、人乳头瘤病毒（HPV）等指标,并将口咽癌分为HPV阳性（p16+）与HPV阴性（p16-）,分别制定了不同的TNM分期标准。2018年,美国国立综合癌症网（NCCN）首次为HPV阳性（p16+）口咽癌制定了诊疗指南。2019年第1版NCCN头颈癌诊疗指南已经发布,其中对口腔口咽癌指南做了部分修订。为临床工作需要,本文结合2版变化进行部分解读。

关键词: AJCC, TNM分期, NCCN, 治疗指南, 口腔癌, 口咽癌

Abstract: In the 8th edition of AJCC Cancer Staging Manual published in 2017, TNM staging criteria for oral and oropharyngeal cancer has added indexes of invasion depth (DOI), extranodal extension (ENE), human papillomavirus (HPV), and classified oropharyngeal cancer into HPV positive (p16+) and HPV negative (p16-), establishing different TNM staging criteria. The National Comprehensive Cancer Network (NCCN) has proposed the diagnosis and treatment guidelines for HPV-positive (p16+) oropharyngeal cancer in 2018. NCCN Guidelines Version 1.2019 for head and neck cancers have been issued in March 6, 2019, among which oral and oropharyngeal cancer algorithms were partially revised. To meet the needs of clinical work, the changes of the two versions of oral and oropharyngeal cancer guidelines were partially interpreted in this paper.

Key words: AJCC, TNM classification, NCCN, Treatment guideline, Oral cavity cancer, Oropharyngeal cancer

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