中国口腔颌面外科杂志

中国口腔颌面外科杂志 ›› 2026, Vol. 24 ›› Issue (3): 255-260.doi: 10.19438/j.cjoms.2026.03.008

• 论著 • 上一篇    下一篇

翻瓣刮治联合赤藓糖醇龈下喷砂治疗种植体周围炎的效果评价

李迎楼1,2,3, 张文涛4, 郭晶1,2,5   

  1. 1.陕西省颅颌面精准医学研究重点实验室,陕西 西安 710000;
    2.陕西省牙颌疾病临床研究中心,陕西 西安 710000;
    3.西安交通大学口腔医院 第三门诊部,陕西 西安 710000;
    4.西安工会医院 口腔科,陕西 西安 710199;
    5.西安交通大学口腔医院 特诊特需科,陕西 西安 710000
  • 收稿日期:2025-09-26 修回日期:2025-12-29 出版日期:2026-05-20 发布日期:2026-06-04
  • 通讯作者: 张文涛,E-mail: 291351722@qq.com
  • 作者简介:李迎楼（1988—）,男,硕士,住院医师,E-mail: shan634357@163.com
  • 基金资助:
    国家自然科学基金（82002875）

Evaluation of the efficacy of flap debridement combined with erythritol subgingival sandblasting in the treatment of peri-implantitis

Li Yinglou1,2,3, Zhang Wentao4, Guo Jing1,2,5   

  1. 1. Key laboratory of Shaanxi Province for Craniofacial Precision Medicine Research. Xi'an 710000;
    2. Clinical Research Center of Shaanxi Province for Dental and Maxillofacial Diseases. Xi'an 710000;
    3. The Third Department of Outpatient, Hospital of Stomatology, Xi'an Jiaotong University. Xi'an 710000;
    4. Department of Stomatology, Xi'an Labor Union Hospital. Xi'an 710199;
    5. Department of Special Clinic, Hospital of Stomatology, Xi'an Jiaotong University. Xi'an 710000, Shaanxi Province, China
  • Received:2025-09-26 Revised:2025-12-29 Online:2026-05-20 Published:2026-06-04

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摘要： 目的: 评价翻瓣刮治联合赤藓糖醇龈下喷砂治疗种植体周围炎（peri-implantitis,PI）的临床效果。方法: 选取西安交通大学口腔医院2023年1月—2025年3月收治的90例PI患者,采用随机数表法分为刮治组（45例,单纯翻瓣刮治）和刮治+喷砂组（45例,翻瓣刮治联合赤藓糖醇龈下喷砂）。比较两组治疗前及治疗后1个月的牙周状况指标[菌斑指数、龈沟出血指数（sulcus bleeding index,SBI）、牙周探诊深度（probing depth,PD）]、龈沟液相关指标[龈沟液量、白细胞介素6（interleukin-6,IL-6）水平、骨桥蛋白水平],治疗后3个月的临床疗效及不同时间点的口腔健康相关生活质量（OHIP-49评分）。结果: 治疗后1个月,两组菌斑指数、SBI、PD、龈沟液量、IL-6及骨桥蛋白水平均较治疗前显著提高（P<0.05）,且刮治+喷砂组改善幅度更大（P<0.05）。治疗后3个月,刮治+喷砂组总有效率（95.56%）显著高于刮治组（80.00%,P<0.05）。治疗后1个月和3个月,两组OHIP-49评分均较治疗前持续降低,且刮治+喷砂组均显著低于刮治组（P<0.05）。结论: 翻瓣刮治联合赤藓糖醇龈下喷砂治疗种植体周围炎可更有效清除菌斑、减轻牙周炎症、降低牙周袋深度,同时缓解炎性反应,提升患者生活质量。

关键词: 种植体周围炎, 翻瓣刮治, 赤藓糖醇, 龈下喷砂, 牙周炎症

Abstract: PURPOSE: To evaluate the clinical efficacy of flap debridement combined with erythritol subgingival sandblasting in the treatment of peri-implantitis(PI). METHODS: A total of 90 patients with PI in Hospital of Stomatology, Xi'an Jiaotong University from January 2023 to March 2025 were selected and divided into the debridement group(n=45, flap debridement alone) and the debridement + sandblasting group (n=45, flap debridement combined with erythritol subgingival sandblasting) using the random number table method. Periodontal status indicators [plaque index, sulcus bleeding index (SBI), probing depth (PD)] and gingival crevicular fluid (GCF) related indicators [GCF volume, interleukin-6 (IL-6), osteopontin] were compared between the two groups before treatment and 1 month after treatment. Clinical efficacy was evaluated 3 months after treatment, and oral health-related quality of life(assessed by OHIP-49 scores) was measured at different time points. RESULTS: One month after treatment, the plaque index, SBI, PD, GCF volume, IL-6 and osteopontin levels in both groups were significantly improved compared with those before treatment (P<0.05), and the improvement amplitude in the debridement + sandblasting group was greater (P<0.05). Three months after treatment, the total effective rate of the debridement + sandblasting group(95.56%) was significantly higher than that of the debridement group (80.00%, P<0.05). At 1 month and 3 months after treatment, the OHIP-49 scores of both groups were continuously decreased compared with those before treatment, and the scores in the debridement + sandblasting group were significantly lower than those in the debridement group (P<0.05). CONCLUSIONS: Flap debridement combined with erythritol subgingival sandblasting for peri-implantitis can more effectively remove plaque, alleviate periodontal inflammation, reduce periodontal pocket depth, relieve inflammatory response, and improve patients' quality of life.

Key words: Peri-implantitis, Flap debridement, Erythritol, Subgingival sandblasting, Periodontal inflammation

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