头颈部多间隙感染严重并发症危险因素的回顾分析

doi:10.19438/j.cjoms.2019.01.007

中国口腔颌面外科杂志 ›› 2019, Vol. 17 ›› Issue (1): 40-43.doi: 10.19438/j.cjoms.2019.01.007

头颈部多间隙感染严重并发症危险因素的回顾分析

黄林剑^1,2, 陈军¹, 严君烈¹, 徐昕¹, 蔡协艺²

1. 浙江大学医学院附属第二医院口腔颌面外科,浙江杭州 310009;
2.上海交通大学医学院附属第九人民医院·口腔医学院口腔外科,国家口腔疾病临床医学研究中心,上海市口腔医学重点实验室,上海市口腔医学研究所,上海 200011;

收稿日期:2018-08-01 修回日期:2018-10-12 出版日期:2019-01-20 发布日期:2019-02-21
通讯作者: 蔡协艺,E-mail: caixieyi27@126.com
作者简介:黄林剑（1987-）,男,硕士,主治医师,E-mail: dshuanglinjian@126.com
基金资助:
国家自然科学基金（81200766）

A retrospective study of risk factors for life-threatening complications of multi-space infections of head and neck

HUANG Lin-jian^1,2, CHEN Jun¹, YAN Jun-lie¹, XU Xin¹, CAI Xie-yi²

1. Department of Oral and Maxillofacial Surgery, The Second Affiliated Hospital, College of Medicine, Zhejiang University. Hangzhou 310009, Zhejiang Province;
2. Department of Oral Surgery, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine; National Clinical Research Center for Oral Diseases; Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology. Shanghai 200011, China;

Received:2018-08-01 Revised:2018-10-12 Online:2019-01-20 Published:2019-02-21

摘要/Abstract

摘要： 目的通过大样本数据分析头颈部多间隙感染严重并发症的危险因素。方法回顾分析2006年2月—2014年7月549例头颈部多间隙感染患者的临床资料。将患者分为糖尿病组和非糖尿病组,统计分析头颈部多间隙感染严重并发症的高危因素。采用SPSS 19.0 软件包对数据进行统计学分析。结果 60~69岁患者头颈部多间隙感染的严重并发症发病率最高,为18.8%;与20~59岁年龄组差异有统计学意义（P=0.027）。多因素方差分析发现,糖尿病组严重并发症发生率是非糖尿病组的2.404倍（P=0.008）。结论高龄和糖尿病是头颈部多间隙感染严重并发症的高危因素,建议在头颈部多间隙感染的诊治过程中,高度关注高龄（60岁以上）和糖尿病患者。

关键词: 头颈部, 间隙感染, 并发症, 糖尿病, 危险因素

Abstract: PURPOSE: To assess the risk factors (age, gender, and underlying systemic diseases) of life-threatening complications of multi-space infections (LCMI) in the head and neck. METHODS: This was a retrospective cohort study that enrolled a sample of patients with multi-space infections who were referred from February 2006 through July 2014. The patients were classified into diabetic and nondiabetic group. Statistical analysis was performed using SPSS 19.0 software package. RESULTS: The highest incidence of LCMI was in 60-69 yr group (18.8%), which was significantly higher than 20-59 yr group (P=0.027). The correlation was further confirmed by multivariable analysis (odds ratio, 1.148; P=0.041). The odds of susceptibility for LCMI development in diabetic patients was 2.404 times as that of nondiabetic patients (odds ratio, 2.404; P=0.008). CONCLUSIONS: Aging and diabetes mellitus increase the risk of development of life-threatening complications in patients with multi-space infections of head and neck. To increase the chance of patient survival, we strongly recommended clinicians pay more attention to patients with multi-space infections, especially those over the age of 60 and/or diabetic patients.

Key words: Head and neck region, Space infection, Complications, Diabetes mellitus, Risk factor

中图分类号:

R782.3

黄林剑, 陈军, 严君烈, 徐昕, 蔡协艺. 头颈部多间隙感染严重并发症危险因素的回顾分析[J]. 中国口腔颌面外科杂志, 2019, 17(1): 40-43.

HUANG Lin-jian, CHEN Jun, YAN Jun-lie, XU Xin, CAI Xie-yi. A retrospective study of risk factors for life-threatening complications of multi-space infections of head and neck[J]. China J Oral Maxillofac Surg, 2019, 17(1): 40-43.

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头颈部多间隙感染严重并发症危险因素的回顾分析

A retrospective study of risk factors for life-threatening complications of multi-space infections of head and neck

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