中国口腔颌面外科杂志

中国口腔颌面外科杂志 ›› 2016, Vol. 14 ›› Issue (4): 366-368.

• 临床总结 • 上一篇    下一篇

CO2激光治疗口腔黏膜浅表病变73例临床分析

黄子贤, 李世豪, 黄志权, 王友元, 张大明, 陈伟良   

  1. 中山大学孙逸仙纪念医院 口腔颌面外科,广东 广州 510120
  • 出版日期:2016-08-20 发布日期:2016-12-08
  • 通讯作者: 黄志权,E-mail: zhiquanhuang1978@126.com
  • 作者简介:黄子贤（1990-）,男,硕士研究生,E-mail: zeahuang@qq.com

Use of carbon dioxide laser in the treatment of superficial oral mucosal lesions: an analysis of 73 clinical cases

HUANG Zi-xian, LI Shi-hao, HUANG Zhi-quan, WANG You-yuan, ZHANG Da-ming, CHEN Wei-liang   

  1. Department of Oral and Maxillofacial Surgery, Sun Yat-sen Memorial Hospital, Sun Yat-Sen University. Guangzhou 510120, Guangdong Province, China
  • Online:2016-08-20 Published:2016-12-08

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摘要： 目的 评价二氧化碳(CO2)激光治疗仪在口腔黏膜浅表病变中的应用安全性和优越性。方法 回顾分析2012年6月—2013年12月应用CO2激光治疗口腔黏膜浅表病变的73例患者,其中包括脉管畸形25例、口腔黏膜白斑22例、口腔黏膜扁平苔藓18例、口腔黏膜及唇红黏膜疣状痣8例。病变范围0.8 cm×0.8 cm~4.0 cm×3.0 cm;同时选取常规手术刀配合电刀切除的口腔黏膜浅表病变20例进行比较。记录所有患者的手术时间和出血量,比较2组患者的手术时间和出血量。采用SPSS19.0软件包对数据进行t检验。结果 73例患者术程顺利,手术时间3~10 min,平均5.5 min,手术平均出血量5 mL;术后无感染,创口均一期愈合;随访1 a,2例口腔黏膜白斑患者术后复发,再次行手术治疗效果良好。对照组手术时间4~15 min,平均9.5 min,手术平均出血量10 mL;20例对照组患者术后无感染,创口一期愈合。结论 应用CO2激光治疗口腔黏膜浅表病变具有出血少、手术视野清晰、复发率低和手术时间短等优点,值得临床推广应用。

关键词: CO2激光, 口腔黏膜病变, 手术治疗

Abstract: PURPOSE: To evaluate the safety and advantages of using carbon dioxide (CO2) laser in treatment of oral mucosal lesions. METHODS: A retrospective analysis was conducted for 73 patients with oral mucosal lesions who received CO2 laser treatment during June 2012 to December 2013, including 25 cases of vascular malformations, 22 cases of oral leukoplakia, 18 cases of oral mucosal lichen planus, and 8 cases of oral mucosal and labial mucosal verrucous nevus. The lesions ranged from 0.8 cm×0.8 cm to 4 cm×3 cm. Twenty cases of oral mucosal lesions using scalpel assisted with electric knife were as control. The operation time and bleeding of all patients were recorded. The operation time and bleeding in 2 groups were compared. Statistical analysis was performed by Student's t test using SPSS19.0 software package. RESULTS: The operation time of CO2 laser group was from 3 to 10 min, with an average of 5.5 min; the average amount of intraoperative bleeding was 5 mL; none of the 73 patients had postoperative infections; and all wounds heal well after surgery. The patients were followed up for 1 year. Two cases of oral leukoplakia showed recurrence after surgery, and a reoperation achieved satisfactory treatment effect. The operation time of the control group was 4 to 15 min, with an average of 9.5 min, and the average amount of intraoperative bleeding was 10 mL. None of the 20 patients had postoperative infections, and the wounds also healed well after surgery. CONCLUSIONS: The application of CO2 laser in treatment of oral mucosal lesions has the advantages of less bleeding, a clear surgical view during surgery, and a shorter operation time.

Key words: Carbon dioxide laser, Oral mucosal lesions, Surgery

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