软腭原发性非特异透明细胞癌1例报告及文献复习

中国口腔颌面外科杂志 ›› 2015, Vol. 13 ›› Issue (2): 190-192.

• 病例报告 • 上一篇

软腭原发性非特异透明细胞癌1例报告及文献复习

徐乙娜, 杨朝晖, 张大明, 王友元, 陈伟良

中山大学孙逸仙纪念医院口腔颌面外科,广东广州 510120

收稿日期:2014-01-17 修回日期:2014-03-24 出版日期:2015-03-20 发布日期:2015-04-23
通讯作者: 杨朝晖,Tel:020-81332099,E-mail: blueocean2013@aliyun.com
作者简介:徐乙娜（1988-）,女,硕士,E-mail: ynxu1028@163.com

Hyalinizing clear cell carcinoma of the soft palate: report of a case and literature review

XU Yi-na, YANG Zhao-hui, ZHANG Da-ming, WANG You-yuan, CHEN Wei-liang

Department of Oral and Maxillofacial Surgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University. Guangzhou 510120, Guangdong Province, China

Received:2014-01-17 Revised:2014-03-24 Online:2015-03-20 Published:2015-04-23

摘要/Abstract

摘要： 报告1例软腭透明细胞癌的治疗效果并复习相关文献。18岁女性患者,右上软腭处出现肿物,行“右上软腭区肿物扩大切除术”后,病理诊断为非特异性透明细胞癌,随访1年未见复发。腺源性非特异透明细胞癌是一种少见的低度恶性肿瘤,症状不明显,确诊依靠病理学检查,必要时做免疫组织化学染色。应与其他含透明细胞的肿瘤如黏液表皮样癌等相鉴别,以扩大切除治疗为主,预后较其他唾液腺肿瘤好。

关键词: 透明细胞癌, 软腭, 病理学

Abstract: To analyze the therapeutic effect of patient suffering from hyalinizing clear cell carcinoma of the soft palate and review of the related literatures. An 18-year-old female patient with a mass on the soft palate was surgically treated in our department. The postoperative pathologic diagnosis was hyalinizing clear cell carcinoma. Glandular hyalinizing clear cell carcinoma is a rare low-grade malignancy without obvious symptoms, usually confirmed by pathology and assisted by immunohistochemistry. Clinically and histopathologically, hyalinizing clear cell carcinoma needs to be differentiated from other malignancies including clear cells such as mucoepidermoid carcinomas et al. It is treated by wide surgical excision and has better prognosis than other salivary gland cancers.

Key words: Clear cell carcinoma, Soft palate, Pathology

中图分类号:

R739.8

徐乙娜, 杨朝晖, 张大明, 王友元, 陈伟良. 软腭原发性非特异透明细胞癌1例报告及文献复习[J]. 中国口腔颌面外科杂志, 2015, 13(2): 190-192.

XU Yi-na, YANG Zhao-hui, ZHANG Da-ming, WANG You-yuan, CHEN Wei-liang. Hyalinizing clear cell carcinoma of the soft palate: report of a case and literature review[J]. China J Oral Maxillofac Surg, 2015, 13(2): 190-192.

参考文献

[1] Milchgrub S, Gnepp DR, Vuitch F, et al. Hyalinizing clear cell carcinoma of salivary gland[J]. Am J Surg Pathol, 1994, 18(1): 74-82.
[2] Ellis GL, Auclair PL. Tumors of the salivary glands [M]. Washington: American Registry of Pathology in collaboration with the Armed Forces Institute of Pathology, 1996: 281-289.
[3] Barnes L, Eveson JW, Reichart P, et al. World Health Organization classification of tumours: pathology and genetics of head and neck tumours [M]. 3rd ed. Lyon: IARC Press, 2005: 227 -228.
[4] Testa D, Galli V, de Rosa G, et al. Clinical and prognostic aspects of laryngeal clear cell carcinoma[J]. J Laryngol Otol, 2005, 119(12): 991-994.
[5] Balakrishnan R, Nayak DR, Pillai S, et al. Hyalinizing clear cell carcinoma of the base of the tongue[J]. J Laryngol Otol, 2002, 116(10): 851-853.
[6] Adil E, Setabutr D, Mikesell K, et al. Hyalinizing clear cell adenocarcinoma of the oropharynx[J]. Head Neck, 2013, 35(6): E184-186.
[7] 王强, 沈毅, 孙坚. 唾液腺透明细胞癌的诊断与治疗[J]. 中国口腔颌面外科杂志, 2008, 6(4): 266-269.
[8] Weinreb I. Hyalinizing clear cell carcinoma of salivary gland: a review and update[J]. Head Neck Pathol,2013,7(Suppl 1):S20-29.
[9] Saleh KA,Nurishmah MI,Firouzeh GN,et al.Primary clear cell carcinoma of minor salivary gland of the soft palate: a case report[J]. Med J Malaysia, 2012, 67(3): 335-336.
[10] Pujary K, Rangarajan S, Nayak DR, et al. Hyalinizing clear cell carcinoma of the base of tongue[J]. Int J Oral Maxillofac Surg, 2008, 37(1): 93-96.
[11] Gon S, Bhattacharyya A, Majumdar B, et al. Post-radiotherapy locoregional recurrence of hyalinizing clear cell carcinoma of palate [J]. J Cancer Res Ther, 2013, 9(2): 281-283.
[12] Solar AA, Schmidt BL, Jordan RC. Hyalinizing clear cell carcinoma:case series and comprehensive review of the literature[J]. Cancer, 2009, 115(1): 75-83.

软腭原发性非特异透明细胞癌1例报告及文献复习

Hyalinizing clear cell carcinoma of the soft palate: report of a case and literature review

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