无水乙醇介入治疗头颈部囊性病变的临床应用现状

中国口腔颌面外科杂志 ›› 2015, Vol. 13 ›› Issue (2): 187-189.

无水乙醇介入治疗头颈部囊性病变的临床应用现状

韩一峰, 范新东

上海交通大学医学院附属第九人民医院放射科,上海 200011

收稿日期:2014-10-30 修回日期:2014-12-09 出版日期:2015-03-20 发布日期:2015-04-23
通讯作者: 范新东,Tel：021-23271699-5555,E-mail:fanxindong2012@aliyun.com
作者简介:韩一峰（1989-）,男,在读硕士研究生,E-mail:hanif1016@hotmail.com

Clinical application of interventional ethanol sclerotherapy in head and neck cystic lesions

HAN Yi-feng, FAN Xin-dong

Department of Radiology, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine. Shanghai 200011, China

Received:2014-10-30 Revised:2014-12-09 Online:2015-03-20 Published:2015-04-23

摘要/Abstract

摘要： 无水乙醇介入治疗在头颈部许多疾病治疗方面都获得了良好的临床效果,为疾病治疗提供了新的选择,选择好适应证能够提高治愈率。无水乙醇介入治疗虽是一种微创、相对安全的方法,但治疗仍存在风险。本文就无水乙醇在治疗头颈部囊性淋巴管畸形、静脉畸形、动脉瘤样骨囊肿等囊性病变方面的临床进展、具体技术要点、可能产生的并发症及防治作一综述。

关键词: 无水乙醇, 介入硬化治疗, 囊性病变

Abstract: As a new treatment option, ethanol interventional therapy has gained satisfactory results in clinical practice in treating head and neck diseases. Although not every patient is suitable for the treatment, ethanol offers considerable promise of controlling the lesions and curing the diseases completely. However, ethanol interventional therapy can lead to some complications, even it's an invasive method. This article discussed the clinical applications of interventional therapy for cervicofacial cystic lymphatic malformations, venous malformations, and aneurysmal bone cysts, as well as the operation principles, the possible complications and management.

Key words: Absolute ethanol, Interventional sclerotherapy, Cystic lesions

中图分类号:

R782

韩一峰, 范新东. 无水乙醇介入治疗头颈部囊性病变的临床应用现状[J]. 中国口腔颌面外科杂志, 2015, 13(2): 187-189.

HAN Yi-feng, FAN Xin-dong. Clinical application of interventional ethanol sclerotherapy in head and neck cystic lesions[J]. China J Oral Maxillofac Surg, 2015, 13(2): 187-189.

参考文献

[1] Borecky N, Gudinchet F, Laurini R, et al. Imaging of cervico-thoracic lymphangiomas in children[J]. Pediatr Radiol,1995,25(2): 127-130.
[2] Mikhail M, Kennedy R, Cramer B, et al. Sclerosing of recurrent lymphangioma using OK-432 [J]. J Pediatr Surg, 1995, 30(8): 1159-1160.
[3] Impellizzeri P, Romeo C, Borruto FA, et al. Sclerotherapy for cervical cystic lymphatic malformations in children. Our experience with computed tomography-guided 98% sterile ethanol insertion and a review of the literature [J]. J Pediatr Surg, 2010, 45(12): 2473-2478.
[4] Mathur NN, Rana I, Bothra R, et al. Bleomycin sclerotherapy in congenital lymphatic and vascular malformations of head and neck [J]. Int J Pediatr Otorhinolaryngol, 2005, 69(1): 75-80.
[5] Cordes BM, Seidel FG, Sulek M, et al. Doxycycline sclerotherapy as the primary treatment for head and neck lymphatic malformations [J]. Otolaryngol Head Neck Surg, 2007, 137(6): 962-964.
[6] Orford J, Barker A, Thonell S, et al. Bleomycin therapy for cystic hygroma [J]. J Pediatr Surg, 1995, 30(9): 1282-1287.
[7] Emran MA, Dubois J, Laberge L, et al. Alcoholic solution of zein (Ethibloc) sclerotherapy for treatment of lymphangiomas in children [J]. J Pediatr Surg, 2006, 41(5): 975-979.
[8] Sanlialp I, Karnak I, Tanyel FC, et al. Sclerotherapy for lymphangioma in children [J]. Int J Pediatr Otorhinolaryngol, 2003, 67(7): 795-800.
[9] Mason KP, Michna E, Zurakowski D, et al. Serum ethanol levels in children and adults after ethanol embolization or sclerotherapy for vascular anomalies [J]. Radiology, 2000, 217(1): 127-132.
[10] Alomari AI, Karian VE, Lord DJ, et al. Percutaneous sclerotherapy for lymphatic malformations: a retrospective analysis of patient-evaluated improvement [J]. J Vasc Interv Radiol, 2006, 17(10): 1639-1648.
[11] Puig S, Aref H, Brunelle F. Double-needle sclerotherapy of lymphangiomas and venous angiomas in children: a simple technique to prevent complications [J]. AJR Am J Roentgenol, 2003, 180(5): 1399-1401.
[12] Wiegand S, Eivazi B, Zimmermann AP, et al. Sclerotherapy of lymphangiomas of the head and neck[J]. Head Neck,2011,33(11): 1649-1655.
[13] Chen WL, Zhang B, Wang JG, et al. Surgical excision of cervicofacial giant macrocystic lymphatic malformations in infants and children[J]. Int J Pediatr Otorhinolaryngol,2009,73(6):833-837.
[14] Richter GT, Braswell L. Management of venous malformations [J]. Facial Plast Surg, 2012, 28(6): 603-610.
[15] Glade RS, Richter GT, James CA, et al. Diagnosis and management of pediatric cervicofacial venous malformations: retrospective review from a vascular anomalies center [J]. Laryngoscope, 2010, 120(2): 229-235.
[16] Eivazi B, Wiegand S, Teymoortash A, et al. Laser treatment of mucosal venous malformations of the upper aerodigestive tract in 50 patients [J]. Lasers Med Sci, 2010, 25(4): 571-576.
[17] Deveikis JP. Percutaneous ethanol sclerotherapy for vascular malformations in the head and neck [J]. Arch Facial Plast Surg, 2005, 7(5): 322-325.
[18] Berenguer B, Burrows PE, Zurakowski D, et al. Sclerotherapy of craniofacial venous malformations: complications and results [J]. Plast Reconstr Surg, 1999, 104(1): 1-11.
[19] 王延安,范新东,郑家伟,等.经皮穿刺DSA引导下无水乙醇硬化治疗头颈部静脉畸形[J].中国口腔颌面外科杂志,2009,7(2): 102-105.
[20] Rimon U, Garniek A, Galili Y, et al. Ethanol sclerotherapy of peripheral venous malformations [J]. Eur J Radiol, 2004, 52(3): 283-287.
[21] Hammer FD, Boon LM, Mathurin P, et al. Ethanol sclerotherapy of venous malformations: evaluation of systemic ethanol contamination [J]. J Vasc Interv Radiol, 2001, 12(5): 595-600.
[22] Ameli NO, Abbassioun K, Azod A, et al. Aneurysmal bone cyst of the skull [J]. Can J Neurol Sci, 1984, 11(4): 466-471.
[23] de Silva MV, Raby N, Reid R. Fibromyxoid areas and immature osteoid are associated with recurrence of primary aneurysmal bone cysts [J]. Histopathology, 2003, 43(2): 180-188.
[24] Clayer M. Injectable form of calcium sulphate as treatment of aneurysmal bone cysts [J]. ANZ J Surg, 2008, 78(5): 366-370.
[25] Varshney MK, Rastogi S, Khan SA, et al. Is sclerotherapy better than intralesional excision for treating aneurysmal bone cysts? [J]. Clin Orthop Relat Res, 2010, 468(6): 1649-1659.
[26] Guibaud L, Herbreteau D, Dubois J, et al. Aneurysmal bone cysts: percutaneous embolization with an alcoholic solution of zein series of 18 cases [J]. Radiology, 1998, 208(2): 369-373.
[27] Lambot-Juhan K, Pannier S, Grevent D, et al. Primary aneurysmal bone cysts in children: percutaneous sclerotherapy with absolute alcohol and proposal of a vascular classification [J]. Pediatr Radiol, 2012, 42(5): 599-605.