侵及颅底的颞下颌关节软骨肉瘤1例报告

doi:10.19438/j.cjoms.2026.05.013

中国口腔颌面外科杂志 ›› 2026, Vol. 24 ›› Issue (5): 527-531.doi: 10.19438/j.cjoms.2026.05.013

侵及颅底的颞下颌关节软骨肉瘤1例报告

宫宇泽^1,2,*, 薛娇^2,*, 王奇民², 姜远政², 邱建忠², 袁荣涛²

1.山东医药大学口腔医学院,山东烟台 264003;
2.康复大学青岛医院（青岛市市立医院）口腔医学中心,山东青岛 266071

收稿日期:2026-04-08 修回日期:2026-05-19 出版日期:2026-09-20 发布日期:2026-10-10
通讯作者: 袁荣涛,E-mail: yuanrongtao@163.com
作者简介:宫宇泽（1998—）,女,硕士,E-mail: gyz_98@163.com;薛娇（1991—）,女,硕士,主治医师,E-mail: xuejiaojj0526@163.com。^*并列第一作者
基金资助:
山东省医药卫生科技项目（202408020636）

Chondrosarcoma in the temporomandibular joint with skull base invasion: a case report

Gong Yuze^1,2, Xue Jiao², Wang Qimin², Jiang Yuanzheng², Qiu Jianzhong², Yuan Rongtao²

1. School of Stomatology, Shandong Medical and Pharmaceutical University. Yantai 264003;
2. Stomatology Center, Qingdao Municipal Hospital; Qingdao Hospital of Rehabilitation University. Qingdao 266071, Shandong Province, China

Received:2026-04-08 Revised:2026-05-19 Online:2026-09-20 Published:2026-10-10

摘要/Abstract

摘要： 颞下颌关节软骨肉瘤临床罕见,肿瘤侵袭颅底时,诊断与外科治疗难度显著提升。本文报告1例累及并破坏颅中窝的颞下颌关节高分化软骨肉瘤病例,计算机辅助手术导航下行颞下窝颅底肿瘤完整切除联合下颌骨髁突切除术,结合影像学、术中所见及免疫组织化学染色总结诊疗要点,并复习国内外相关文献,为本类罕见病变的临床处置提供参考。

关键词: 颞下颌关节, 软骨肉瘤, 颅底, 髁突切除术

Abstract: Temporomandibular joint chondrosarcoma is clinically rare, and its diagnosis and surgical management become significantly more challenging when the tumor invades the skull base. This article reported a case of highly differentiated temporomandibular joint chondrosarcoma involving and destroying the middle cranial fossa. The complete resection of the skull base tumor in the temporal fossa was performed under computer-assisted surgical navigation, combined with mandibular condylectomy. Key diagnostic and therapeutic principles are summarized based on imaging findings, intraoperative observations, and pathological immunohistochemical results, with a review of relevant domestic and international literature, providing reference for the clinical management of this rare lesion.

Key words: Temporomandibular joint, Chondrosarcoma, Skull base, Mandibular condylectomy

中图分类号:

R739.8

宫宇泽, 薛娇, 王奇民, 姜远政, 邱建忠, 袁荣涛. 侵及颅底的颞下颌关节软骨肉瘤1例报告[J]. 中国口腔颌面外科杂志, 2026, 24(5): 527-531.

Gong Yuze, Xue Jiao, Wang Qimin, Jiang Yuanzheng, Qiu Jianzhong, Yuan Rongtao. Chondrosarcoma in the temporomandibular joint with skull base invasion: a case report[J]. China J Oral Maxillofac Surg, 2026, 24(5): 527-531.

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侵及颅底的颞下颌关节软骨肉瘤1例报告

Chondrosarcoma in the temporomandibular joint with skull base invasion: a case report

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